ArticleJournal of clinical medicine2020
Macular Thickness Decrease in Asymptomatic Subjects at High Genetic Risk of Developing Alzheimer's Disease: An OCT Study.
Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 35 citations in OpenAlex.
- Exploratory Analysis of APOE ε4-Stratified Associations Between Plasma Alzheimer's Biomarkers and Retinal Imaging Metrics in Cognitively Normal Adults.Translational vision science & technology · 2026Article
- Assessing Retinal Thickness and Associations with Cognitive Function in Women with History of Preeclampsia.Eye and brain · 2026Article
- Ocular changes as potential biomarkers for early diagnosis of Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Review
- Age-Related Retinal Layer Thickness Changes Measured by OCT inInternational journal of molecular sciences · 2024Article
- Retinal Vascular and Structural Changes in the Murine Alzheimer'sBiomolecules · 2024Article
- Association of retinal optical coherence tomography metrics and polygenic risk scores with cognitive function and future cognitive decline.The British journal of ophthalmology · 2024Article
- Structural and Functional Retinal Changes in Patients with Mild Cognitive Impairment with and without Diabetes.Journal of clinical medicine · 2023Article
- Potential Retinal Biomarkers in Alzheimer's Disease.International journal of molecular sciences · 2023Review
- The Association ofJournal of clinical medicine · 2023Article
- Exploratory Longitudinal Study of Ocular Structural and Visual Functional Changes in Subjects at High Genetic Risk of Developing Alzheimer's Disease.Biomedicines · 2023Article
- The Eye as a Diagnostic Tool for Alzheimer's Disease.Life (Basel, Switzerland) · 2023Review
- Optical Coherence Tomography: Retinal Imaging Contributes to the Understanding of Brain Pathology in Classical Galactosemia.Journal of clinical medicine · 2023Article
- Retinal Tissue Shows Glial Changes in a Dravet Syndrome Knock-in Mouse Model.International journal of molecular sciences · 2023Article
- Early visual alterations in individuals at-risk of Alzheimer's disease: a multidisciplinary approach.Alzheimer's research & therapy · 2023Article
- Longitudinal Analysis of the Retina and Choroid in Cognitively Normal Individuals at Higher Genetic Risk of Alzheimer Disease.Ophthalmology. Retina · 2022Article
- Association Between Retinal Layer Thickness and Cognitive Decline in Older Adults.JAMA ophthalmology · 2022Article
- Retinal Vascular Study Using OCTA in Subjects at High Genetic Risk of Developing Alzheimer's Disease and Cardiovascular Risk Factors.Journal of clinical medicine · 2022Article
- The relationship between retinal layers and brain areas in asymptomatic first-degree relatives of sporadic forms of Alzheimer's disease: an exploratory analysis.Alzheimer's research & therapy · 2022Article
- Characterization of Retinal Drusen in Subjects at High Genetic Risk of Developing Sporadic Alzheimer's Disease: An Exploratory Analysis.Journal of personalized medicine · 2022Article
- Application of Structural Retinal Biomarkers to Detect Cognitive Impairment in a Primary Care Setting.Journal of Alzheimer's disease reports · 2022Article
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
Abstract
In this case control study, we examined the retinal thickness of the different layers in the macular region and peripapillary retinal nerve fiber layer (RNFL) with optical coherence tomography (OCT) in healthy cognitive subjects (from 51 to 74 years old) at high genetic risk for developing Alzheimer's disease (AD). Thirty-five subjects with a family history of Alzheimer disease (AD) (FH+) and ApoE ɛ4 carriers and 29 age-matched control subjects without a family history of AD (FH-) and ApoE ɛ4 non-carriers were included. Compared to FH- ApoE ɛ4 non-carriers, in FH+ ApoE ɛ4 carriers, there were statistically significant decreases (
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.