Evidence map›Paper›PMID 32503261›Full record

ArticleMolecules (Basel, Switzerland)2020

Comparison of Phytochemicals, Antioxidant, and In Vitro Anti-Alzheimer Properties of Twenty-Seven

Piya Temviriyanukul, Varittha Sritalahareuthai, Kriskamol Na Jom, Butsara Jongruaysup, Somying Tabtimsri, Kanchana Pruesapan, Sirinapa Thangsiri, Woorawee Inthachat, Dalad Siriwan, Somsri Charoenkiatkul and 1 more

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Pharmaceuticals (Basel, Switzerland) · 2022
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. The Effect of Sacred Lotus (Molecules (Basel, Switzerland) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Piya TemviriyanukulInstitute of Nutrition, Mahidol University, Salaya, Phuttamonthon, Nakhon Pathom 73170, Thailand.ORCID 0000-0002-7590-7024
Varittha SritalahareuthaiInstitute of Nutrition, Mahidol University, Salaya, Phuttamonthon, Nakhon Pathom 73170, Thailand.
Kriskamol Na JomDepartment of Food Science and Technology, Faculty of Agro-Industry, Kasetsart University, Chatuchak, Bangkok 10900, Thailand.
Butsara JongruaysupOffice of Sericulture Conservation and Standard Conformity Assessment, The Queen Sirikit Department of Sericulture, Ministry of Agriculture and Cooperatives, Bangkok 10900, Thailand.
Somying TabtimsriThe Queen Sirikit Department of Sericulture Center (Kanchanaburi), Nong Ya, Mueang Kanchanaburi District, Kanchanaburi 71000, Thailand.
Kanchana PruesapanPlant Varieties Protection Office, Department of Agriculture, Ministry of Agriculture and Cooperatives, Bangkok 10900, Thailand.
Sirinapa ThangsiriInstitute of Nutrition, Mahidol University, Salaya, Phuttamonthon, Nakhon Pathom 73170, Thailand.
Woorawee InthachatInstitute of Nutrition, Mahidol University, Salaya, Phuttamonthon, Nakhon Pathom 73170, Thailand.
Dalad SiriwanInstitute of Food Research and Product Development, Kasetsart University, Chatuchak, Bangkok 10900, Thailand.
Somsri CharoenkiatkulInstitute of Nutrition, Mahidol University, Salaya, Phuttamonthon, Nakhon Pathom 73170, Thailand.
Uthaiwan SuttisansaneeInstitute of Nutrition, Mahidol University, Salaya, Phuttamonthon, Nakhon Pathom 73170, Thailand.ORCID 0000-0001-5887-6329

Funding

Biodiversity-Based Economy Development Office (BEDO) 22/2561Grants-in-Aid from JSPS Core to-Core Program B. Asia-Africa Science Platforms -
6 · The paper itself

Abstract

Alzheimer's disease (AD) is a progressive neurodegenerative disorder. To fight the disease, natural products, including mulberry, with antioxidant activities and inhibitory activities against key enzymes (acetylcholinesterase (AChE), butyrylcholinesterase (BChE), and beta-secretase 1 (BACE-1)) are of interest. However, even in the same cultivars, mulberry trees grown in different populated locations might possess disparate amounts of phytochemical profiles, leading to dissimilar health properties, which cause problems when comparing different cultivars of mulberry. Therefore, this study aimed to comparatively investigate the phytochemicals, antioxidant activities, and inhibitory activities against AChE, BChE, and BACE-1, of twenty-seven

Indexed as

AcetylcholinesteraseAlzheimer DiseaseAmyloid Precursor Protein SecretasesAntioxidantsAspartic Acid EndopeptidasesButyrylcholinesteraseEnzyme InhibitorsGPI-Linked ProteinsHumansMorusPhytochemicalsPlant ExtractsAcetylcholinesteraseACHE protein, humanAmyloid Precursor Protein SecretasesAntioxidantsAspartic Acid EndopeptidasesBACE1 protein, humanBCHE protein, humanButyrylcholinesteraseEnzyme InhibitorsGPI-Linked ProteinsPhytochemicalsPlant Extractsanthocyanidinsanthocyaninsanti-Alzheimer propertiesantioxidantbeta-secretase 1Morus species

Identifiers

PMID32503261
PMCPMC7321130

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.