ArticleOral oncology2020
Summary from an international cancer seminar focused on human papillomavirus (HPV)-positive oropharynx cancer, convened by scientists at IARC and NCI.
Open access · hybridAbstract readConference Proceedings
In one paragraph
Article in Oral oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 4 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 4 pooled it
7.1field-weighted citation impact, top 1% of its field
What it found
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Who cites it
33 citing papers in PubMed, 4 syntheses or guidelines pooled it, 62 citations in OpenAlex.
- Human Papillomavirus-Attributable Head and Neck Cancers in India-A Systematic Review and Meta-Analysis.JCO global oncology · 2024Pooled it
- Clinical assessment for the detection of oral cavity cancer and potentially malignant disorders in apparently healthy adults.The Cochrane database of systematic reviews · 2021Pooled it
- Pooled it
- Diagnostic tests for oral cancer and potentially malignant disorders in patients presenting with clinically evident lesions.The Cochrane database of systematic reviews · 2021Pooled it
- Molecular insights and therapeutic innovations in low-risk human papillomavirus-associated cutaneous wart.Molecular biology reports · 2026Review
- PREVALENCE, CHARACTERISTICS AND TREATMENT OUTCOMES OF HPV POSITIVE OROPHARYNGEAL CARCINOMA IN AFRICA: A SYSTEMATIC REVIEW AND META-ANALYaSIS.Annals of Ibadan postgraduate medicine · 2026Article
- In Vitro Model Characterizing Carcinogenic Progression of HPV-Positive Oropharyngeal Cancer.Cancers · 2026Article
- Impact of Nutritional Status on Severe Radiation-Induced Mucositis in Oropharyngeal Cancer Patients Undergoing Chemo-Radiotherapy.Nutrients · 2025Article
- HPV associated oropharyngeal cancer in eastern China over the last 7 years: is the incidence in chinese truly exceptionally low?BMC public health · 2025Article
- Impact of screening for human papillomavirus-positive oropharyngeal cancers: a microsimulation-based modeling study.Journal of the National Cancer Institute · 2025Article
- Comparing In Vitro Virucidal Efficacy of Commercially Available Mouthwashes Against Native High-Risk Human Papillomavirus Types 16 and 18.Microorganisms · 2025Article
- Global burden of head and neck cancer: Epidemiological transitions, inequities, and projections to 2050.Frontiers in oncology · 2025Article
- Clinical features and prognostic analysis of 120 patients with oropharyngeal squamous cell carcinoma: a hospital-based real-world study.Frontiers in oncology · 2025Article
- Biplex quantitative PCR to detect transcriptionally active human papillomavirus 16 from patient saliva.BMC cancer · 2024Article
- Radiation-induced changes in energy metabolism result in mitochondrial dysfunction in salivary glands.Scientific reports · 2024Article
- Global epidemiologic patterns of oropharyngeal cancer incidence trends.Journal of the National Cancer Institute · 2023Article
- Findings from a Malaysian multicentre study on oropharyngeal squamous cell carcinoma.Infectious agents and cancer · 2023Article
- Uneven Expression of 20 Human Papillomavirus Genes Associated with Oropharyngeal Carcinoma.Rambam Maimonides medical journal · 2023Article
- Review
- A risk prediction model for head and neck cancers incorporating lifestyle factors, HPV serology and genetic markers.International journal of cancer · 2023Article
Corrections and comments
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Authors and funding
31 authors at 20 institutions in 9 countries.
Aimée R KreimerDivision of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD, United States. Electronic address: kreimera@mail.nih.gov.
Anil K ChaturvediDivision of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD, United States. Electronic address: chaturva@mail.nih.gov.
Laia AlemanyCatalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Barcelona, Spain; Epidemiology and Public Health, Centro de Investigación Biomédica en Red: Epidemiología y Salud Pública (CIBERESP), Instituto de Salud Carlos III, Madrid, Spain. Electronic address: lalemany@iconcologia.net.
Devasena AnantharamanRajiv Gandhi Centre for Biotechnology, Trivandrum, India. Electronic address: devasena@rgcb.res.in.
Freddie BrayInternational Agency for Research on Cancer, Lyon, France. Electronic address: Brayf@iarc.fr.
Mary CarringtonBasic Science Program, Frederick National Laboratory for Cancer Research, Frederick, MD, United States; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, United States. Electronic address: carringm@mail.nih.gov.
John DoorbarUniversity of Cambridge, Cambridge, United Kingdom. Electronic address: jd121@cam.ac.uk.
Gypsyamber D'SouzaJohns Hopkins University Bloomberg School of Public Health, Baltimore, MD, United States. Electronic address: Gdsouza2@jhu.edu.
Carole FakhryJohns Hopkins University Bloomberg School of Public Health, Baltimore, MD, United States; Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins School of Medicine, Baltimore, MD, United States. Electronic address: cfakhry@jhmi.edu.
Robert L FerrisUPMC Hillman Cancer Center, Pittsburgh, PA, United States. Electronic address: ferrrl@upmc.edu.
Maura GillisonThe University of Texas MD Anderson Cancer Center, Houston, TX, United States. Electronic address: mgillison@mdanderson.org.
D Neil HayesThe University of Tennessee Health Science Center, Memphis, TN, United States. Electronic address: Neil.Hayes@uthsc.edu.
Allan HildesheimDivision of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD, United States. Electronic address: hildesha@exchange.nih.gov.
Shao Hui HuangUniversity of Toronto, Princess Margaret Hospital, Toronto, Ontario, Canada. Electronic address: ShaoHui.Huang@rmp.uhn.ca.
Luiz P KowalskiA.C. Camargo Cancer Center, São Paulo, Brazil. Electronic address: lp_kowalski@uol.com.br.
Krystle A Lang KuhsVanderbilt University Medical Center, Nashville, TN, United States. Electronic address: krystle.kuhs@vumc.org.
James LewisVanderbilt University Medical Center, Nashville, TN, United States. Electronic address: james.lewis@vanderbilt.edu.
Douglas R LowyLaboratory of Cellular Oncology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD, United States; Office of the Director, National Cancer Institute, NIH, Bethesda, MD, United States. Electronic address: lowyd@mail.nih.gov.
Hisham MehannaInstitute for Head and Neck Studies and Education, University of Birmingham, Birmingham, United Kingdom. Electronic address: h.mehanna@bham.ac.uk.
Andy NessNIHR Bristol Biomedical Research Centre, University of Bristol NHS Foundation Trust and University of Bristol, Bristol, United Kingdom. Electronic address: Andy.Ness@bristol.ac.uk.
Michael PawlitaGerman Cancer Research Center (DKFZ), Heidelberg, Germany. Electronic address: m.pawlita@dkfz-heidelberg.de.
Maisa PinheiroDivision of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD, United States. Electronic address: maisa.pinheiro@nih.gov.
John SchillerLaboratory of Cellular Oncology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD, United States. Electronic address: schillej@dc37a.nci.nih.gov.
Meredith S ShielsDivision of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD, United States. Electronic address: shielsms@mail.nih.gov.
Joseph TotaDivision of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD, United States. Electronic address: joseph.tota@nih.gov.
Lisa MirabelloDivision of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD, United States. Electronic address: mirabellol@mail.nih.gov.
Saman WarnakulasuriyaKing's College London, London, United Kingdom; WHO Collaborating Centre for Oral Cancer, United Kingdom. Electronic address: saman.warne@kcl.ac.uk.
Tim WaterboerGerman Cancer Research Center (DKFZ), Heidelberg, Germany. Electronic address: T.Waterboer@dkfz-heidelberg.de.
William WestraIcahn School of Medicine at Mount Sinai, New York, NY, United States. Electronic address: william.westra@mountsinai.org.
Stephen ChanockDivision of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Bethesda, MD, United States. Electronic address: hanocks@mail.nih.gov.
Paul BrennanInternational Agency for Research on Cancer, Lyon, France. Electronic address: gep@iarc.fr.
National Cancer Institute · USCentre international de recherche sur le cancer · FRGerman Cancer Research Center · DEJohns Hopkins University · USNational Institutes of Health · USUniversity of Cambridge · GBVanderbilt University Medical Center · USAC Camargo Hospital · BRIcahn School of Medicine at Mount Sinai · USInstituto de Salud Carlos III · ESLondon Cancer · GBOffice of the Director · USRagon Institute of MGH, MIT and Harvard · USRajiv Gandhi Centre for Biotechnology · INThe University of Texas MD Anderson Cancer Center · USUniversity Hospitals Bristol NHS Foundation Trust · GBUniversity of Birmingham · GBUniversity of Tennessee Health Science Center · USUniversity of Toronto · CAUPMC Health System · US
Funding
Effects of genetic polymorphism in MHC, KIR, and related loci on human diseaseZIABC010791 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI CARRINGTON, MARY N. · 2009 to 2025
$18.2MVanderbilt Clinical Oncology Research Career Development ProgramK12CA090625 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Debra L. Friedman, Paula Jill Hurley · 2001 to 2026
$16.9MPapillomavirus Virion Proteins and VaccinesZIABC010579 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI LOWY, DOUGLAS R. · 2009 to 2025
$15.4MHuman Papillomavirus-Specific Biomarkers for the Prediction of Oropharyngeal Cancer RecurrenceK07CA218247 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI KUHS, KRYSTLE A. · 2018 to 2021
$594kCancer Research UK 28754Medical Research Council MC_PC_13050Medical Research Council MC_U117584278Medical Research Council MR/S024409/1NCI NIH HHS K07 CA218247NCI NIH HHS K12 CA090625World Health Organization 001
Abstract
Cancer of the oropharynx has attracted considerable attention in recent years given: (1) an increasing incidence in selected populations over the past three decades; (2) the discovery of human papillomavirus (HPV) infection as the driver of the increase, as opposed to the traditional risk factors such as tobacco (smoking and chewing) and alcohol; and (3) the promise of new prevention and treatment strategies. As a result of such developments, the International Agency for Research on Cancer (IARC) and the US National Cancer Institute (NCI), convened the fourth Cancer Seminar meeting in November 2018 to focus on this topic. This report summarizes the proceedings: a review of recent science on the descriptive epidemiology, etiology, biology, genetics, early detection, pathology and treatment of HPV-positive oropharyngeal cancer, and the formulation of key research questions to be addressed.
Indexed as
AgedHumansMiddle AgedNational Cancer Institute (U.S.)Oropharyngeal NeoplasmsPapillomaviridaePapillomavirus InfectionsUnited StatesEtiologyGeneticsHPVOropharynx cancerPreventionScreeningTherapy
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