ArticlePloS one2020
Higher levels of disease-related knowledge reduce medical acceleration in patients with inflammatory bowel disease.
Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- Management of Inflammatory Bowel Disease Using E-health Technologies: A Systematic Review and Meta-Analysis.Journal of Crohn's & colitis · 2023Pooled it
- The Effectiveness of Patient Training in Inflammatory Bowel Disease Knowledge via Instagram: Randomized Controlled Trial.Journal of medical Internet research · 2022Trial
- Health Literacy in Inflammatory Bowel Disease: A Systematic Review of Health Outcomes, Predictors and Barriers.Journal of clinical medicine · 2025Review
- The gut-brain connection: Inflammatory bowel disease increases risk of acute ischemic stroke.Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences · 2025Article
- Factors Influencing Decision-Making Preferences Among Patients with Inflammatory Bowel Disease: A Cross-Sectional Study in China.Patient preference and adherence · 2025Article
- Article
- Knowledge in Inflammatory Bowel Disease: Translation to Portuguese, Validation, and Clinical Application of the IBD-KNOW Questionnaire.GE Portuguese journal of gastroenterology · 2024Article
- Coping Strategies and Inflammatory Bowel Disease: A Narrative Review.Journal of clinical medicine · 2024Review
- Knowledge, attitude, and practice of patients living with inflammatory bowel disease: A cross-sectional study.World journal of gastroenterology · 2023Article
- People Living with Inflammatory Bowel Disease Want Multidisciplinary Healthcare: A Qualitative Content Analysis.Journal of clinical psychology in medical settings · 2022Article
- Assessment of patients' understanding of inflammatory bowel diseases: Development and validation of a questionnaire.United European gastroenterology journal · 2022Article
- Determinants of disease-specific knowledge among children with inflammatory bowel disease and their parents: A multicentre study.World journal of gastroenterology · 2021Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimsThe disease-related knowledge levels in patients with inflammatory bowel disease (IBD) are important because it could affect the self-management ability and adaptive coping strategies. We set out to determine whether higher levels of disease-related knowledge reduce medical acceleration.
methodsWe evaluated the levels of disease-related knowledge in all patients at the time of enrollment for SNUBH IBD cohort using the validated IBD-KNOW questionnaire. Clinical data were prospectively collected and the factors related to step-up therapy were analyzed. Step-up therapy was defined as the new use of corticosteroids, immunomodulators, or biologics after the enrollment.
resultsBetween April 2017 and January 2019, 298 patients were enrolled (mean age, 39.8 years; males, 69.5%); 193 patients (64.8%) had ulcerative colitis and 105 (35.2%) had Crohn's disease. The mean disease duration was 35.8 months. During the mean follow-up of 14.7 months, 90 patients (30.2%) underwent step-up therapy and 208 (69.8%) underwent continuous therapy. The prevalence of continuous therapy increased with increasing IBD-KNOW scores (p for trend = 0.019). Cox proportional hazards analysis revealed that high IBD-KNOW scores (≥ 16) (hazards ratio [HR]: 0.498, 95% confidence interval [CI]: 0.276-0.897, p = 0.020) was negatively associated with the step-up therapy.
conclusionsHigher disease-related knowledge could reduce the requirement of step-up therapy in IBD. The IBD-KNOW score was independently predictive of step-up therapy.
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