Evidence map›Paper›PMID 32502157›Full record

ArticlePloS one2020

Pre-operative gastrocnemius lengths in gait predict outcomes following gastrocnemius lengthening surgery in children with cerebral palsy.

Apoorva Rajagopal, Łukasz Kidziński, Alec S McGlaughlin, Jennifer L Hicks, Scott L Delp, Michael H Schwartz

Abstract read
In one paragraph

Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. An Efficient Framework for Personalizing EMG-Driven Musculoskeletal Models Based on Reinforcement Learning.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Apoorva RajagopalDepartment of Mechanical Engineering, Stanford University, Stanford, CA, United States of America.ORCID 0000-0002-7915-7048
Łukasz KidzińskiDepartment of Bioengineering, Stanford University, Stanford, CA, United States of America.
Alec S McGlaughlinDepartment of Bioengineering, Stanford University, Stanford, CA, United States of America.
Jennifer L HicksDepartment of Bioengineering, Stanford University, Stanford, CA, United States of America.
Scott L DelpDepartment of Mechanical Engineering, Stanford University, Stanford, CA, United States of America.ORCID 0000-0002-9643-7551
Michael H SchwartzCenter for Gait and Motion Analysis, Gillette Children's Specialty Healthcare, St. Paul, MN, United States of America.

Funding

Training CoreU54EB020405 · NIBIB · STANFORD UNIVERSITY · PI DELP, SCOTT L · 2014 to 2018
$11.6M
Tech-DevelopmentP2CHD065690 · NICHD · STANFORD UNIVERSITY · PI DELP, SCOTT L · 2015 to 2019
$5.4M
National Center for Simulation in Rehabilitation ResearchR24HD065690 · NICHD · STANFORD UNIVERSITY · PI DELP, SCOTT L · 2010 to 2014
$4.2M
NIBIB NIH HHS U54 EB020405NICHD NIH HHS P2C HD065690NICHD NIH HHS R24 HD065690
6 · The paper itself

Abstract

Equinus deformity is one of the most common gait deformities in children with cerebral palsy. We examined whether estimates of gastrocnemius length in gait could identify limbs likely to have short-term and long-term improvements in ankle kinematics following gastrocnemius lengthening surgery to correct equinus. We retrospectively analyzed data of 891 limbs that underwent a single-event multi-level surgery (SEMLS), and categorized outcomes based on the normalcy of ankle kinematics. Limbs with short gastrocnemius lengths that received a gastrocnemius lengthening surgery as part of a SEMLS (case limbs) were 2.2 times more likely than overtreated limbs (i.e., limbs who did not have short lengths, but still received a lengthening surgery) to have a good surgical outcome at the follow-up gait visit (good outcome rate of 71% vs. 33%). Case limbs were 1.2 times more likely than control limbs (i.e., limbs that had short gastrocnemius lengths but no lengthening surgery) to have a good outcome (71% vs. 59%). Three-fourths of the case limbs with a good outcome at the follow-up gait visit maintained this outcome over time, compared to only one-half of the overtreated limbs. Our results caution against over-prescription of gastrocnemius lengthening surgery and suggest gastrocnemius lengths can be used to identify good surgical candidates.

Indexed as

GaitCerebral PalsyChildEquinus DeformityHumansLegMuscle, SkeletalOutcome and Process Assessment, Health CareRetrospective Studies

Identifiers

PMID32502157
PMCPMC7274436

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.