Observational studyMedicine2020
Metabolic syndrome, depression, and fibromyalgia syndrome prevalence in patients with irritable bowel syndrome: A case-control study.
Observational study in Medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 18 citations in OpenAlex.
- The Relationship Between Irritable Bowel Syndrome and Metabolic Syndrome: A Systematic Review and Meta-Analysis of 49,662 Individuals.Endocrinology, diabetes & metabolism · 2025Pooled it
- Examining the Association Between Overweight, Obesity, and Irritable Bowel Syndrome: A Systematic Review and Meta-Analysis.Nutrients · 2024Pooled it
- Trial
- Insulin, Glucose and Lipid Biomarkers as Possible Risk Factors for Functional Somatic Disorder: A Five-Year Follow-Up of the DanFunD Cohort.Journal of clinical medicine · 2026Article
- Cardiometabolic Burden of Irritable Bowel Syndrome: A Case-Control Analysis of Metabolic Syndrome Clustering.Journal of epidemiology and global health · 2026Article
- Social Rhythms, Depressive Symptoms, and Quality of Life: An Unbreakable Bond in an Older Adult Sample.International journal of environmental research and public health · 2026Observational
- Article
- Poor self-rated health in individuals with irritable bowel syndrome but no increased 10-year cardiovascular risk: results from a Swedish population-based screening program.Frontiers in cardiovascular medicine · 2026Article
- Altered core depressive symptom balance in post-COVID fatigue: reduced depressed mood in an exploratory matched historical-control study.Frontiers in psychiatry · 2026Article
- Long-term risk of irritable bowel syndrome associated with MASLD, MASLD type and different cardiometabolic risk factors: a large-scale prospective cohort study.BMC gastroenterology · 2025Article
- The impact of changes in fibromyalgia diagnosis criteria: using NAMCS data (2010-2019) to identify trends.BMC rheumatology · 2025Article
- Editorial: Neuroimaging in psychiatry 2023: mood disorders.Frontiers in psychiatry · 2025Article
- Can adaptive hyperactivation result in a positive score on the Mood Disorder Questionnaire? Evidence from a case-control study over a community survey.Frontiers in psychiatry · 2025Article
- Association between celiac disease and fibromyalgia and their severity: a cross-sectional study.PeerJ · 2024Article
- Associations between irritable bowel syndrome and non-alcoholic fatty liver disease: A systematic review.World journal of hepatology · 2023Article
- Are patients with polycystic ovary syndrome more prone to irritable bowel syndrome?Endocrine connections · 2022Article
- Guts Imbalance Imbalances the Brain: A Review of Gut Microbiota Association With Neurological and Psychiatric Disorders.Frontiers in medicine · 2022Review
- Epidemiology, Clinical Features, and Prescribing Patterns of Irritable Bowel Syndrome in Taiwan.Frontiers in pharmacology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although both metabolic syndrome (MetS) and irritable bowel syndrome (IBS) have been linked with altered gut microbiota, only a few studies investigated the association between them. Hence, we aimed to evaluate the prevalence of MetS along with depression and fibromyalgia syndrome (FMS) in IBS patients.This was a case-control study in which 3808 consecutive patients who attended outpatient clinics of Erzurum Regional Training and Research Hospital between May 2019 and August 2019 were evaluated in terms of IBS with Rome-IV criteria. Out of 486 patients who were diagnosed as IBS, 176 patients were excluded for various reasons. Control subjects were randomly selected from IBS-negative subjects. MetS was diagnosed based on International Diabetes Federation criteria. Depression, anxiety disorder, and FMS were assessed via Hamilton Depression Scale, Beck Anxiety Inventory, and American College of Rheumatology criteria, respectively. Blood samples were obtained to measure biochemical parameters.Study group included 310 IBS patients, and control group included 304 subjects. The prevalence of the MetS was significantly higher among IBS patients compared with controls (36.8% vs 21.7%, respectively, P = .006). The rate of obesity was 18.1% among IBS subjects, and 10.2% in the controls. The prevalence of fibromyalgia (30% vs 3%, respectively, P < .001), anxiety-disorder (39.7% vs 10.2%, P < .001) and depression (8.1% vs 4.9%, P < .001) were significantly higher in IBS group than controls.Metabolic syndrome and obesity were significantly more frequent in IBS patients compared with controls. FMS, anxiety disorder, and depression were also more common among IBS patients.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.