Evidence map›Paper›PMID 32501772›Full record

ReviewAnnual review of biomedical engineering2020

Integrated Biophysical Modeling and Image Analysis: Application to Neuro-Oncology.

Andreas Mang, Spyridon Bakas, Shashank Subramanian, Christos Davatzikos, George Biros

Abstract readReview
In one paragraph

Review in Annual review of biomedical engineering, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

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  6. Identifiability and model selection frameworks for models of high-grade glioma response to chemoradiation.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2025
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  16. Ensemble Inversion for Brain Tumor Growth Models With Mass Effect.IEEE transactions on medical imaging · 2023
    Article
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  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Andreas MangDepartment of Mathematics, University of Houston, Houston, Texas 77204, USA; email: andreas@math.uh.edu.
Spyridon BakasDepartment of Mathematics, University of Houston, Houston, Texas 77204, USA; email: andreas@math.uh.edu.
Shashank SubramanianOden Institute of Computational Engineering and Sciences, The University of Texas at Austin, Austin, Texas 78712, USA; email: shashank@oden.utexas.edu, gbiros@acm.org.
Christos DavatzikosCenter for Biomedical Image Computing and Analytics (CBICA); Department of Radiology; and Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA; email: sbakas@upenn.edu, christos.davatzikos@pennmedicine.upenn.edu.
George BirosOden Institute of Computational Engineering and Sciences, The University of Texas at Austin, Austin, Texas 78712, USA; email: shashank@oden.utexas.edu, gbiros@acm.org.

Funding

Phenotypic Diversity in COVID-19UL1TR001878 · NCATS · UNIVERSITY OF PENNSYLVANIA · PI FITZGERALD, GARRET A · 2016 to 2025
$102.4M
Statistical atlases of brain tumor MRI:do imaging phenotypes predict progression?R01NS042645 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI DAVATZIKOS, CHRISTOS · 2002 to 2024
$8.7M
Cancer imaging phenomics software suite: application to brain and breast cancerU24CA189523 · NCI · UNIVERSITY OF PENNSYLVANIA · PI DAVATZIKOS, CHRISTOS, KONTOS, DESPINA · 2015 to 2019
$3.2M
Biomedical Image Computing and Informatics ClusterS10OD023495 · OD · UNIVERSITY OF PENNSYLVANIA · PI DAVATZIKOS, CHRISTOS · 2017 to 2017
$1.9M
NCATS NIH HHS UL1 TR001878NCI NIH HHS U24 CA189523NIH HHS S10 OD023495NINDS NIH HHS R01 NS042645
6 · The paper itself

Abstract

Central nervous system (CNS) tumors come with vastly heterogeneous histologic, molecular, and radiographic landscapes, rendering their precise characterization challenging. The rapidly growing fields of biophysical modeling and radiomics have shown promise in better characterizing the molecular, spatial, and temporal heterogeneity of tumors. Integrative analysis of CNS tumors, including clinically acquired multi-parametric magnetic resonance imaging (mpMRI) and the inverse problem of calibrating biophysical models to mpMRI data, assists in identifying macroscopic quantifiable tumor patterns of invasion and proliferation, potentially leading to improved (

Indexed as

Image Processing, Computer-AssistedAlgorithmsAnimalsBiophysicsBrainBrain NeoplasmsCalibrationGenome, HumanGliomaHumansMagnetic Resonance ImagingModels, NeurologicalModels, TheoreticalNeoplasmsPrognosisbiophysical modelingglioblastomaimage analysismodel calibrationmulti-parametric imagingradiomicstumor growth

Identifiers

PMID32501772
PMCPMC7520881

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.