Evidence map›Paper›PMID 32501718›Full record

ArticleNano letters2020

Selective Binding of Complex Glycans and Glycoproteins in Water by Molecularly Imprinted Nanoparticles.

Milad Zangiabadi, Yan Zhao

Open access · greenAbstract read
In one paragraph

Article in Nano letters, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 41 citations in OpenAlex.

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  14. Substrate Protection in Controlled Enzymatic Transformation of Peptides and Proteins.Chembiochem : a European journal of chemical biology · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Milad ZangiabadiDepartment of Chemistry, Iowa State University, Ames, Iowa 50011-3111, United States.
Yan ZhaoDepartment of Chemistry, Iowa State University, Ames, Iowa 50011-3111, United States.ORCID 0000-0003-1215-2565
Iowa State University · US

Funding

Biomimetic Receptors for Small Hydrophobic Drugs, Carbohydrates, and OligopeptidesR01GM113883 · NIGMS · IOWA STATE UNIVERSITY · PI ZHAO, YAN · 2015 to 2018
$1.1M
NIGMS NIH HHS R01 GM113883
6 · The paper itself

Abstract

Synthetic receptors to recognize biological glycans are in great need for modern glycoscience and technology, but their design and synthesis have been a daunting challenge due to strong solvation of carbohydrates in water and structural complexity of the guest. Molecular imprinting in surfactant micelles with amide cross-linkers provides a convenient one-pot method to prepare nanoparticle receptors for glycosides, glycans, and glycoproteins, taking advantage of hydrogen-bonding interactions near the surfactant/water interface. Biologically competitive micromolar binding affinities were obtained in water and subtle structural differences of glycans could be distinguished.

Indexed as

Molecular ImprintingNanoparticlesGlycoproteinsPolysaccharidesWaterGlycoproteinsPolysaccharidesWaterbindingglycanmicellemolecular imprintingmolecular recognitionreceptor

Identifiers

PMID32501718
PMCPMC7472588
OpenAlexW3033928933

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.