Evidence map›Paper›PMID 32501614›Full record

ArticleMagnetic resonance in medicine2020

Tensor image enhancement and optimal multichannel receiver combination analyses for human hyperpolarized

Hsin-Yu Chen, Adam W Autry, Jeffrey R Brender, Shun Kishimoto, Murali C Krishna, Maryam Vareth, Robert A Bok, Galen D Reed, Lucas Carvajal, Jeremy W Gordon and 9 more

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

  1. Review
  2. Article
  3. Clinical Translation of HyperpolarizedAJNR. American journal of neuroradiology · 2025
    Review
  4. Article
  5. Article
  6. Quo Vadis HyperpolarizedZeitschrift fur medizinische Physik · 2025
    Review
  7. Current methods for hyperpolarized [1-Magnetic resonance in medicine · 2024
    Review
  8. HyperpolarizedMagnetic resonance in medicine · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. Hyperpolarized δ-[1-Scientific reports · 2023
    Article
  13. Tensor denoising of multidimensional MRI data.Magnetic resonance in medicine · 2023
    Article
  14. Article
  15. Article
  16. Kinetic analysis of multi-resolution hyperpolarizedMagnetic resonance in medicine · 2022
    Article
  17. Article
  18. Post-Acquisition HyperpolarizedDiagnostics (Basel, Switzerland) · 2022
    Article
  19. HyperpolarizedCancers · 2022
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Hsin-Yu ChenDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, California, USA.ORCID 0000-0002-2765-1685
Adam W AutryDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, California, USA.
Jeffrey R BrenderCenter for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.
Shun KishimotoCenter for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.
Murali C KrishnaCenter for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA.
Maryam VarethDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, California, USA.
Robert A BokDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, California, USA.
Galen D ReedGE Healthcare, Chicago, Illinois, USA.
Lucas CarvajalDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, California, USA.
Jeremy W GordonDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, California, USA.ORCID 0000-0003-2760-4886
Mark van CriekingeDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, California, USA.
David E KorenchanDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, California, USA.ORCID 0000-0001-6152-5896
Albert P ChenGE Healthcare, Chicago, Illinois, USA.
Duan XuDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, California, USA.
Yan LiDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, California, USA.
Susan M ChangDepartment of Neurological Surgery, University of California, San Francisco, California, USA.
John KurhanewiczDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, California, USA.
Peder E Z LarsonDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, California, USA.ORCID 0000-0003-4183-3634
Daniel B VigneronDepartment of Radiology and Biomedical Imaging, University of California, San Francisco, California, USA.

Funding

Project 4: Multi-modality Metabolic Imaging for Monitoring Molecular Sub-types of GliomaP01CA118816 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Pavithra Viswanath · 2007 to 2026
$44.7M
TR&D3: Open-Source Tools for Processing Hyperpolarized MR DataP41EB013598 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI DUAN XU · 2011 to 2026
$19.9M
Overhauser Enhanced Magnetic Resonance Imaging (OMRI)ZIABC010477 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI CHERUKURI, MURALI · 2009 to 2025
$16.1M
Training Program in Translational Brain Tumor ResearchT32CA151022 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Joseph F Costello · 2010 to 2026
$6.6M
Supplement for Development and Translation of Specialized Hyperpolarized C-13 MRI Methods for Alzheimer's DiseaseU01EB026412 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI GORDON, JEREMY WILLIAM, VIGNERON, DANIEL B · 2019 to 2023
$6.6M
Translating HP 13C MRI as a Novel Paradigm for Assessing Drug Target InhibitionR01CA183071 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HURD, RALPH EUGENE, MUNSTER, PAMELA N. · 2014 to 2018
$3.3M
Hyperpolarized C-13 MRI for Early Detection of Aggressive Prostate Cancer in Active Surveillance PatientsU01CA232320 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BOK, ROBERT A, VIGNERON, DANIEL B · 2019 to 2023
$3.2M
NCI NIH HHS P01 CA118816NCI NIH HHS R01 CA183071NCI NIH HHS T32 CA151022NCI NIH HHS U01 CA232320NIBIB NIH HHS P41 EB013598NIBIB NIH HHS U01 EB026412
6 · The paper itself

Abstract

purposeWith the initiation of human hyperpolarized

methodsA data-driven processing framework for dynamic HP

resultsTRI and ORC techniques together provided a 63-fold mean apparent signal-to-noise ratio (aSNR) gain for receiver arrays and a 31-fold gain for single-element configurations, which particularly improved quantification of the lower-SNR-[

conclusionOverall, this combined approach was effective across imaging targets and receiver configurations and could greatly benefit ongoing and future HP

Indexed as

Image EnhancementMagnetic Resonance ImagingCarbon IsotopesChildHumansMagnetic Resonance SpectroscopyPyruvic AcidSignal-To-Noise RatioCarbon IsotopesPyruvic Acidcancer imaginghyperpolarized C-13 pyruvatetensor rank truncation image enhancement

Identifiers

PMID32501614
PMCPMC7718428

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.