Evidence map›Paper›PMID 32501470›Full record

ArticleBioscience reports2020

To study the effect of oxygen carrying capacity on expressed changes of erythrocyte membrane protein in different storage times.

Huan Wang, Han-Wei Wei, Hua-Chun Shen, Zhen-Zhou Li, Yong Cheng, Li-Shuang Duan, Lei Yin, Jun Yu, Jian-Rong Guo

Open access · goldAbstract readComparative Study
In one paragraph

Article in Bioscience reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Huan Wang *Department of Anesthesiology, Shanghai Gongli Hospital, The Second Military Medical University, Shanghai 200135, P.R. China.
Han-Wei Wei *Department of Anesthesiology, Shanghai Gongli Hospital, The Second Military Medical University, Shanghai 200135, P.R. China.
Hua-Chun ShenHwaMei Hospital, University of Chinese Academy of Sciences, Zhejiang 315010, P.R. China.
Zhen-Zhou LiDepartment of Anesthesiology, Shanghai Gongli Hospital, The Second Military Medical University, Shanghai 200135, P.R. China.
Yong ChengDepartment of Anesthesiology, Shanghai Gongli Hospital, The Second Military Medical University, Shanghai 200135, P.R. China.
Li-Shuang DuanDepartment of Anesthesiology, Shanghai Gongli Hospital, The Second Military Medical University, Shanghai 200135, P.R. China.
Lei YinDepartment of Anesthesiology, Shanghai Gongli Hospital, The Second Military Medical University, Shanghai 200135, P.R. China.
Jun YuDepartment of Anesthesiology, Yijishan Hospital, Wannan Medical College, Wuhu 241001, P.R. China.
Jian-Rong GuoDepartment of Anesthesiology, Shanghai Gongli Hospital, The Second Military Medical University, Shanghai 200135, P.R. China.
Second Military Medical University · CNUniversity of Chinese Academy of Sciences · CNWannan Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Erythrocyte membrane is crucial to maintain the stability of erythrocyte structure. The membrane protein on the surface of erythrocyte membrane enables erythrocyte to have plasticity and pass through the microcirculation without being blocked or destroyed. Decreased deformability of erythrocyte membrane protein will lead to a series of pathological and physiological changes such as tissue and organ ischemia and hypoxia. Therefore, this research collected 30 cases of healthy blood donors, and explored erythrocyte stored at different times relating indicators including effective oxygen uptake (Q), P50, 2,3-DPG, Na+-k+-ATP. Erythrocyte morphology was observed by electron microscopy. Western blot and immunofluorescence assay were used to detect membrane protein EPB41, S1P, GLTP, SPPL2A expression changes of erythrocyte. To explore the effective carry oxygen capacity of erythrocyte at different storage time resulting in the expression change of erythrocyte surface membrane protein.

Indexed as

Blood DonorsBlood Preservation2,3-DiphosphoglycerateAspartic Acid EndopeptidasesCarrier ProteinsCytoskeletal ProteinsErythrocyte MembraneHumansMembrane ProteinsOxygenSodium-Potassium-Exchanging ATPaseSphingosine-1-Phosphate ReceptorsTime Factors2,3-DiphosphoglycerateAspartic Acid EndopeptidasesCarrier ProteinsCytoskeletal Proteinserythrocyte membrane band 4.1 proteinGLTP protein, humanMembrane ProteinsOxygenSodium-Potassium-Exchanging ATPaseSphingosine-1-Phosphate ReceptorsSPPL2a protein, humanerythrocyteMembrane proteinoxygen carrying capacitystorage time

Identifiers

PMID32501470
PMCPMC7317602
OpenAlexW3033143533

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.