Evidence map›Paper›PMID 32501287›Full record

ArticleJournal of cell science2020

Epb41l5 interacts with Iqcb1 and regulates ciliary function in zebrafish embryos.

Tiffany Yu, Miho Matsuda

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cell science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Tiffany YuDepartment of Cell Biology and Molecular Medicine, Rutgers New Jersey Medical School, Newark, NJ 07302, USA.
Miho MatsudaDepartment of Cell Biology and Molecular Medicine, Rutgers New Jersey Medical School, Newark, NJ 07302, USA miho.matsuda@mssm.edu.ORCID 0000-0002-7495-5905
Rutgers, The State University of New Jersey · US

Funding

Regulation of cell polarity by Wnt signalingR35GM122492 · NIGMS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Sergei Sokol · 2017 to 2026
$5.0M
The Role of EPB41L5 in Regulation of Cilia FunctionR03HD094980 · NICHD · RBHS-NEW JERSEY MEDICAL SCHOOL · PI MATSUDA, MIHO · 2019 to 2020
$164k
NICHD NIH HHS R03 HD094980NIGMS NIH HHS R35 GM122492
6 · The paper itself

Abstract

Erythrocyte protein band 4.1 like 5 (EPB41L5) is an adaptor protein beneath the plasma membrane that functions to control epithelial morphogenesis. Here we report a previously uncharacterized role of EPB41L5 in controlling ciliary function. We found that EPB41L5 forms a complex with IQCB1 (previously known as NPHP5), a ciliopathy protein. Overexpression of EPB41L5 reduced IQCB1 localization at the ciliary base in cultured mammalian epithelial cells. Conversely,

Indexed as

CiliaZebrafishAnimalsCentrosomeCytoskeletal ProteinsEye ProteinsZebrafish ProteinsCytoskeletal Proteinsepb41l5 protein, zebrafishEye ProteinsZebrafish ProteinsCiliaEPB41L5Epithelial morphogenesisIQCB1Left–right patterningZebrafish

Identifiers

PMID32501287
PMCPMC7338265
OpenAlexW3026195698

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.