Evidence map›Paper›PMID 32501216›Full record

ArticleeLife2020

Flexible motor sequence generation during stereotyped escape responses.

Yuan Wang, Xiaoqian Zhang, Qi Xin, Wesley Hung, Jeremy Florman, Jing Huo, Tianqi Xu, Yu Xie, Mark J Alkema, Mei Zhen and 1 more

Abstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

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  10. Hierarchical behavior control by a single class of interneurons.Proceedings of the National Academy of Sciences of the United States of America · 2024
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Yuan Wang *Hefei National Laboratory for Physical Sciences at the Microscale, Center for Integrative Imaging, School of Life Sciences, University of Science and Technology of China, Hefei, China.ORCID 0000-0002-0471-5754
Xiaoqian Zhang *Hefei National Laboratory for Physical Sciences at the Microscale, Center for Integrative Imaging, School of Life Sciences, University of Science and Technology of China, Hefei, China.ORCID 0000-0001-5636-7950
Qi Xin *Hefei National Laboratory for Physical Sciences at the Microscale, Center for Integrative Imaging, School of Life Sciences, University of Science and Technology of China, Hefei, China.ORCID 0000-0002-5748-8057
Wesley HungSamuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Canada.
Jeremy FlormanDepartment of Neurobiology, University of Massachusetts Medical School, Worcester, United States.ORCID 0000-0001-7578-3511
Jing HuoHefei National Laboratory for Physical Sciences at the Microscale, Center for Integrative Imaging, School of Life Sciences, University of Science and Technology of China, Hefei, China.
Tianqi XuHefei National Laboratory for Physical Sciences at the Microscale, Center for Integrative Imaging, School of Life Sciences, University of Science and Technology of China, Hefei, China.
Yu XieHefei National Laboratory for Physical Sciences at the Microscale, Center for Integrative Imaging, School of Life Sciences, University of Science and Technology of China, Hefei, China.ORCID 0000-0003-3624-0252
Mark J AlkemaDepartment of Neurobiology, University of Massachusetts Medical School, Worcester, United States.ORCID 0000-0002-1311-5179
Mei ZhenSamuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Canada.ORCID 0000-0003-0086-9622
Quan WenHefei National Laboratory for Physical Sciences at the Microscale, Center for Integrative Imaging, School of Life Sciences, University of Science and Technology of China, Hefei, China.ORCID 0000-0003-0268-8403

Funding

Molecular and neuronal mechanisms of complex behaviorsR01GM084491 · NIGMS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI ALKEMA, MARK · 2008 to 2017
$3.0M
The gut brain axis: microbial impact on neural functionR01NS107475 · NINDS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI ALKEMA, MARK · 2018 to 2022
$1.8M
Chinese Academy of Sciences Strategic Priority Research Program XDB39000000CIHR 154274Key Area R&D Program of Guangdong Province 2018B030338001National Science Foundation of China NSFC-31471051National Science Foundation of China NSFC-91632102NIGMS NIH HHS R01 GM084491NINDS NIH HHS R01 NS107475Strategic Priority Research Program of Chinese Academy of Sciences XDPB10
6 · The paper itself

Abstract

Complex animal behaviors arise from a flexible combination of stereotyped motor primitives. Here we use the escape responses of the nematode

Indexed as

Escape ReactionAnimalsBehavior, AnimalCaenorhabditis elegansElectrical SynapsesFemaleMaleMotor ActivityNervous System Physiological PhenomenaNeural InhibitionC. elegansescape responsefeedforward excitationmotor sequence generationmutual inhibitionneurosciencewinner-take-all

Identifiers

PMID32501216
PMCPMC7338056

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.