Evidence map›Paper›PMID 32501140›Full record

ArticleGut microbes2020

Freeze-dried fecal samples are biologically active after long-lasting storage and suited to fecal microbiota transplantation in a preclinical murine model of

Julie Reygner, Christine Charrueau, Johanne Delannoy, Camille Mayeur, Véronique Robert, Céline Cuinat, Thierry Meylheuc, Aurélie Mauras, Jérémy Augustin, Ioannis Nicolis and 5 more

Registry-linked trialAbstract read
In one paragraph

Article in Gut microbes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06250413 (Lyophilized Capsulated Autological Fecal Microbial Transplant to Restore Gut Microbiome After Treatment With Antibiotics), which is not on this map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06250413 nanot yet recruitingnot on this mapstarted 2024, after this paper: background citation

Lyophilized Capsulated Autological Fecal Microbial Transplant to Restore Gut Microbiome After Treatment With Antibiotics

TypeinterventionalSponsorOtto HelveRan2024 to 2027Enrolled40ConditionsMicrobial Colonization, Antibiotic Side EffectArmsFMT, Placebo, Amox Clav
3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Evaluation of the effects of different formulations of protectants on the preservation of the microbiota in fecal microbiota transplantation.International microbiology : the official journal of the Spanish Society for Microbiology · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Human microbiota-associated animal models: a review.Frontiers in cellular and infection microbiology · 2025
    Review
  12. Review
  13. Synergy betweenMolecular therapy. Methods & clinical development · 2024
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Prolonged storage reduces viability ofFrontiers in microbiology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Julie ReygnerINSERM UMR-S1139, Université de Paris , Paris, France.
Christine CharrueauINSERM U1267 CNRS UMR 8258, Chimie ParisTech, PSL Research University, Université de Paris , Paris, France.ORCID 0000-0001-7768-4605
Johanne DelannoyINSERM UMR-S1139, Université de Paris , Paris, France.
Camille MayeurMicalis Institute, AgroParisTech, INRAE, Université Paris-Saclay , Jouy-en-Josas, France.
Véronique RobertMicalis Institute, AgroParisTech, INRAE, Université Paris-Saclay , Jouy-en-Josas, France.
Céline CuinatMicalis Institute, AgroParisTech, INRAE, Université Paris-Saclay , Jouy-en-Josas, France.
Thierry MeylheucMicalis Institute, AgroParisTech, INRAE, Université Paris-Saclay , Jouy-en-Josas, France.
Aurélie MaurasINSERM UMR-S1139, Université de Paris , Paris, France.ORCID 0000-0003-2975-9275
Jérémy AugustinDepartment of Pathology, APHP Sorbonne Université, Pitie-Salpetriere Hospital , Paris, France.ORCID 0000-0001-8194-0624
Ioannis NicolisUniversité de Paris , Paris, France.ORCID 0000-0001-7207-7689
Morgane ModouxINSERM UMR-S1139, Université de Paris , Paris, France.
Francisca JolyDepartment of Gastroenterology and Nutrition Support, APHP, Beaujon Hospital , Clichy, France.
Anne-Judith Waligora-DuprietINSERM UMR-S1139, Université de Paris , Paris, France.ORCID 0000-0002-4885-5302
Muriel ThomasMicalis Institute, AgroParisTech, INRAE, Université Paris-Saclay , Jouy-en-Josas, France.ORCID 0000-0002-7608-3274
Nathalie KapelINSERM UMR-S1139, Université de Paris , Paris, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fecal microbiota transplantation is now recommended for treating recurrent forms of

Indexed as

Fecal Microbiota TransplantationFecesFreeze DryingGastrointestinal MicrobiomeAdministration, OralAnimalsBacteriaBiological Specimen BanksCapsulesClostridium InfectionsDisease Models, AnimalFatty Acids, VolatileFreezingGerm-Free LifeMiceTime FactorsCapsulesFatty Acids, VolatileClostridioides difficileFecal microbiota transplantfreeze-dried microbiotafrozen microbiotapre-clinical model

Identifiers

PMID32501140
PMCPMC7524285

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.