Evidence map›Paper›PMID 32500748›Full record

ArticleAnnals of medicine2020

Relationship of adverse events to quality of anticoagulation control in atrial fibrillation patients with diabetes: real-world data from the FANTASIIA Registry.

Amaya García-Fernández, María Asunción Esteve-Pastor, Inmaculada Roldán-Rabadán, Javier Muñiz, Martín Ruiz Ortiz, Ángel Cequier, Vicente Bertomeu-Martínez, Lina Badimón, Déborah Otero, Manuel Anguita and 3 more

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in Annals of medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. DNA methylation profiling of CD04Annals of medicine and surgery (2012) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 9 institutions in 3 countries.

Amaya García-FernándezDepartment of Cardiology, Alicante General University Hospital, Sanitary and Biomedical Investigation Institute of Alicante (ISABIAL-FISABIO), Alicante, Spain.
María Asunción Esteve-PastorDepartment of Cardiology, Hospital Clínico Universitario Virgen de la Arrixaca, IMIB-Arrixaca, CIBERCV, Murcia, Spain.
Inmaculada Roldán-RabadánDepartment of Cardiology, University Hospital La Paz, Madrid, Spain.
Javier MuñizInstituto Universitario de Ciencias de la Salud de la Universidad de A Coruña; Instituto de Investigación Biomédica de A Coruña (INIBIC), CIBERCV, Spain.
Martín Ruiz OrtizDepartment of Cardiology, University Hospital Reina Sofia, Cordoba, Spain.
Ángel CequierDepartment of Cardiology, University Hospital of Bellvitge, Barcelona, CIBERCV, Spain.
Vicente Bertomeu-MartínezDepartment of Cardiology, University Hospital San Juan de Alicante, Alicante, Spain.
Lina BadimónCardiovascular Research Centre(CSIC-ICCC), Barcelona, CIBERCV, Spain.
Déborah OteroODDS, S.L., A Coruña, Spain.
Manuel AnguitaDepartment of Cardiology, University Hospital Reina Sofia, Cordoba, Spain.
Gregory Y H LipLiverpool Centre for Cardiovascular Science, University of Liverpool and Liverpool Heart & Chest Hospital, Liverpool, UK.
Francisco MarínDepartment of Cardiology, Hospital Clínico Universitario Virgen de la Arrixaca, IMIB-Arrixaca, CIBERCV, Murcia, Spain.
FANTASIIA investigators
Centro de Investigación en Red en Enfermedades Cardiovasculares · ESHospital Universitario Reina Sofía · ESBellvitge University Hospital · ESCentro de Investigación Biomédica en Red · ESFundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana · ESHospital Universitario La Paz · ESHospital Universitario Virgen de la Arrixaca · ESHospital Universitari Sant Joan D'Alacant · ESLiverpool Heart and Chest Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAtrial fibrillation (AF) patients with diabetes (DM) have high risk of cardiovascular events. PURPOSE: To compare clinical characteristics, adverse outcomes and quality of anticoagulation in AF patients regarding DM status.

methodsAF patients from FANTASIIA registry were included. Baseline characteristics and comorbidities were recorded. After 2-years follow-up, the association between adverse events and DM was evaluated.

results1956 patients (mean age 73.8 ± 9.5 years, 56% male) were analyzed; 574 (29.3%) had DM. Diabetic patients had also high prevalence of hypertension (90.6% vs 76.1%;

conclusionAF Diabetic patients have higher comorbidities and poorer TTR than nondiabetic patients. Low TTR was associated with adverse events. The risk of cardiovascular outcomes was higher in DM patients, with independent association between DM and mortality risk.

Indexed as

AgedAged, 80 and overAnticoagulantsAtrial FibrillationCase-Control StudiesComorbidityDiabetes MellitusFactor Xa InhibitorsFemaleHumansMaleMiddle AgedProspective StudiesRegistriesAnticoagulantsFactor Xa InhibitorsAtrial fibrillationdiabetes mellitusoral anticoagulationrisk factors

Identifiers

PMID32500748
PMCPMC7877972
OpenAlexW3033392883

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.