ReviewJournal of child psychology and psychiatry, and allied disciplines2021
Research Review: Pediatric anxiety disorders - what have we learnt in the last 10 years?
Review in Journal of child psychology and psychiatry, and allied disciplines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07366580 (TOUCHMinds), which is not on this map. Cited by 61 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
TOUCHMinds: An RCT on Help-seeking for Adolescent Anxiety
Who cites it
61 citing papers in PubMed, 2 syntheses or guidelines pooled it, 143 citations in OpenAlex.
- Drawing and visual art interventions for anxiety in children aged 5-12: a systematic review and meta-analysis of randomised controlled trials.BMJ paediatrics open · 2026Pooled it
- Repetitive Transcranial Magnetic Stimulation for Generalized Anxiety Disorder: A Systematic Literature Review and Meta-Analysis.The international journal of neuropsychopharmacology · 2022Pooled it
- Circulating endocannabinoids in children and adolescents: associations with anxiety and the impact of selective serotonin reuptake inhibitors.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2025Trial
- Neural Substrates of Emotion Processing and Cognitive Control Over Emotion in Youth Anxiety: An RDoC-Informed Study Across the Clinical to Nonclinical Continuum of Severity.Journal of the American Academy of Child and Adolescent Psychiatry · 2025Trial
- Acute Neurofunctional Effects of Escitalopram in Pediatric Anxiety: A Double-Blind, Placebo-Controlled Trial.Journal of the American Academy of Child and Adolescent Psychiatry · 2021Trial
- Escitalopram in Adolescents With Generalized Anxiety Disorder: A Double-Blind, Randomized, Placebo-Controlled Study.The Journal of clinical psychiatry · 2020Trial
- Resting-State Cortical Network and Subcortical Hyperconnectivity in Youth With Generalized Anxiety Disorder in the ABCD Study.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2026Article
- Longitudinal Changes in Infant Attention-Related Brain Networks and Fearful Temperament.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2026Article
- Pharmacogenetic-Guided Antidepressant Prescribing in Adolescents (PGx-GAP): Study Protocol for a Randomized Controlled Trial.Journal of personalized medicine · 2026Article
- Infant sensory gating and a developmental cascade to autistic traits and anxiety.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Review
- Repetitive transcranial magnetic stimulation: advances for psychiatric disorders.Frontiers in psychiatry · 2026Review
- Neural Efficiency as a Brain-Wide Signature of Pediatric Anxiety and a Biomarker for Treatment Response.The American journal of psychiatry · 2026Article
- Bridging the gap: unveiling key links between autism and anxiety symptoms in autistic children and youth using a network analysis in pooled data from four countries.Child and adolescent mental health · 2025Article
- Practice-based research examining effectiveness of exposure-based CBT for youth in a community mental health setting.Journal of mood and anxiety disorders · 2025Article
- The benefits of sharing house-tree-fire-water-person drawings with parents when their anxious child is in sandplay therapy.Psychology and psychotherapy · 2025Article
- Involving Parents in the Management and Treatment of Youth Anxiety.Current psychiatry reports · 2025Review
- Transdiagnostic Symptom Domains Have Distinct Patterns of Association With Head Motion During Multimodal Imaging in Children.Biological psychiatry global open science · 2025Article
- ADHD Children Take More Time to Inhibit Automatic Responses: A Comparison with Anxiety Disorders Using NEPSY-II.Children (Basel, Switzerland) · 2025Article
- Quality Improvement Initiative to Implement Anxiety Screening for Children and Teens With Headache and Epilepsy.Neurology. Clinical practice · 2025Article
- Acceptance and commitment therapy as a transdiagnostic approach to adolescents with different anxiety disorders: study protocol.European child & adolescent psychiatry · 2025Article
1 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundAnxiety disorders first emerge during the critical developmental periods of childhood and adolescence. This review synthesizes recent findings on the prevalence, risk factors, and course of the anxiety disorders; and their neurobiology and treatment.
methodsFor this review, searches were conducted using PubMed, PsycINFO, and clinicaltrials.gov. Findings related to the epidemiology, neurobiology, risk factors, and treatment of pediatric anxiety disorders were then summarized.
findingsAnxiety disorders are high prevalence, and early-onset conditions associated with multiple risk factors including early inhibited temperament, environment stress, and structural and functional abnormalities in the prefrontal-amygdala circuitry as well as the default mode and salience networks. The anxiety disorders are effectively treated with cognitive behavioral therapy (CBT), selective serotonin reuptake inhibitors (SSRIs), and serotonin-norepinephrine reuptake inhibitors (SNRIs).
conclusionsAnxiety disorders are high prevalence, early-onset conditions associated with a distinct neurobiological fingerprint, and are consistently responsive to treatment. Questions remain regarding who is at risk of developing anxiety disorders as well as the way in which neurobiology predicts treatment response.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.