Evidence map›Paper›PMID 32500287›Full record

ReviewCurrent cardiology reports2020

Challenges and Controversies in the Management of ACS in Elderly Patients.

Waleed T Kayani, Mahin R Khan, Matthew R Deshotels, Hani Jneid

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current cardiology reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.6field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
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  5. Review
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  8. Article
  9. Acute coronary syndromes.Lancet (London, England) · 2022
    Review
  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Waleed T KayaniSection of Cardiology, Department of Internal Medicine, Baylor College of Medicine, Houston, TX, USA. kayani@bcm.edu.
Mahin R KhanDivision of Cardiology, McLaren-Flint/Michigan State University, Flint, MI, USA.
Matthew R DeshotelsDepartment of Medicine, Baylor College of Medicine, Houston, TX, USA.
Hani JneidSection of Cardiology, Department of Internal Medicine, Baylor College of Medicine, Houston, TX, USA.
Baylor College of Medicine · USMcLaren Regional Medical Center · USMichael E. DeBakey VA Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewElderly patients presenting with acute coronary syndrome (ACS) represent a challenging patient population. A high index of suspicion is needed for their diagnosis, as they are less likely to present with typical anginal symptoms compared to their younger counterparts. RECENT

findingsDisrupted coronary plaques with superimposed thrombosis are the predominant pathophysiology of ACS; however, an increased proportion of calcified nodules is encountered in elderly patients. Emergent reperfusion and revascularization remain the mainstay treatment for ST-elevation myocardial infarction or cardiogenic shock. In elderly patients with NSTE-ACS, a routine invasive strategy is generally superior to an ischemia-guided strategy, and the safety of an early invasive strategy has also been recently demonstrated. When treating elderly ACS patients with antiplatelet and antithrombotic therapies, close attention to co-morbidities, frailty and the balance of ischemia-bleeding risk should be undertaken, and medication doses should be carefully adjusted. Overall, elderly patients with ACS remain undertreated with evidence-based therapies, experience worse outcomes, and represent an opportunity for enhancing and mitigating healthcare disparities.

Indexed as

Acute Coronary SyndromeAgedAge FactorsAgingAngina PectorisGeriatric AssessmentHumansAcute coronary syndromeAntiplatelet therapyElderlyOctogenariansOlder adults

Identifiers

PMID32500287
OpenAlexW3033233756

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.