Evidence map›Paper›PMID 32500115›Full record

ArticleTherapeutic advances in ophthalmology

Plastic modification of human cornea

Antonio Medina, Peter R Greene

Open access · diamondAbstract read
In one paragraph

Article in Therapeutic advances in ophthalmology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Antonio MedinaResearch Laboratory of Electronics (RLE), Massachusetts Institute of Technology, 77 Massachusetts Ave., Cambridge, MA 02139, USA.ORCID https://orcid.org/0000-0002-9538-0311
Peter R GreeneBioengineering, BGKT Consulting Ltd., Huntington, NY, USA.
Massachusetts Institute of Technology · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe purpose of this report is to quantify how pressure applied to the human cornea, either physiological or intentional, affects its curvature. In particular, how pneumatic procedures flatten the central cornea and keep it flat over time, thereby decreasing the patient's myopia.

methodsA viscoelastic model is developed for plastic deformation which gives us the basic governing equations of the elastic and plastic strain of corneal stroma. The model is applied to data from corneas of six patients who underwent pneumatic keratology (NEumatica Keratologia) to reduce their myopia.

resultsThe model shows corneal dimensional stability for long periods of time after NEumatica Keratologia that decay with an exponential time constant. Separate equations are developed that relate corneal plastic strain to the pressure applied and its duration

conclusionsThe model proposed is a good description of NEumatica Keratologia outcomes. Practical applications include the long-term stable correction of myopia with refractive procedures. High myopia subjects can benefit from this procedure because NEumatica Keratologia corrects and protects the central cornea radius by stretching the peripheral cornea.

Indexed as

corneamyopiaNEumatica Keratologianoninvasivepneumatic keratologystrainviscoelasticity

Identifiers

PMID32500115
PMCPMC7243390
OpenAlexW3026895969

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.