Evidence map›Paper›PMID 32500090›Full record

ArticleOpen forum infectious diseases2020

Chagas Disease in the New York City Metropolitan Area.

Crystal Zheng, Orlando Quintero, Elizabeth K Revere, Michael B Oey, Fabiola Espinoza, Yoram A Puius, Diana Ramirez-Baron, Carlos R Salama, Luis F Hidalgo, Fabiana S Machado and 5 more

Open access · goldAbstract read
In one paragraph

Article in Open forum infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Sex Differences in Cardiac Pathology of SARS-CoV2 Infected andFrontiers in cardiovascular medicine · 2022
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 11 institutions in 2 countries.

Crystal ZhengSection of Infectious Diseases, Tulane University School of Medicine, New Orleans, Louisiana, USA.
Orlando QuinteroDivision of Infectious Diseases and Geographic Medicine, Stanford University School of Medicine, Stanford, California, USA.
Elizabeth K RevereDivision of Infectious Diseases, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell University, Manhasset, New York, USA.
Michael B OeyDivision of Infectious Diseases, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell University, Manhasset, New York, USA.
Fabiola EspinozaMetro Infectious Diseases Consultants, Burr Ridge, Illinois, USA.
Yoram A PuiusDivision of Infectious Diseases, Montefiore Medical Center-Albert Einstein College of Medicine, Bronx, New York, USA.
Diana Ramirez-BaronGrameen VidaSana Clinic, Queens, New York, USA.
Carlos R SalamaDivision of Infectious Diseases, Elmhurst Hospital Center-Icahn School of Medicine at the Mount Sinai Hospital, Queens, New York, USA.
Luis F HidalgoDivision of Cardiovascular Medicine, University of Kentucky College of Medicine, Lexington, Kentucky, USA.
Fabiana S MachadoFederal University of Minas Gerais, Belo Horizonte, Brazil.
Omar SaeedDivision of Cardiology, Montefiore Medical Center-Albert Einstein College of Medicine, Bronx, New York, USA.
Jooyoung ShinDivision of Cardiology, Montefiore Medical Center-Albert Einstein College of Medicine, Bronx, New York, USA.
Snehal R PatelDivision of Cardiology, Montefiore Medical Center-Albert Einstein College of Medicine, Bronx, New York, USA.
Christina M CoyleDivision of Infectious Diseases, Albert Einstein College of Medicine and Jacobi Medical Center, Bronx, New York, USA.
Herbert B TanowitzDivision of Infectious Diseases, Albert Einstein College of Medicine and Jacobi Medical Center, Bronx, New York, USA.
Albert Einstein College of Medicine · USMontefiore Medical Center · USDonald & Barbara Zucker School of Medicine at Hofstra/Northwell · USHofstra University · USInfectious Disease Consultants · USJacobi Medical Center · USMount Sinai Hospital · USStanford University · USTulane University · USUniversidade Federal de Minas Gerais · BRUniversity of Kentucky · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChagas disease, caused by the parasite

methodsWe review our experience managing 60 patients with Chagas disease in hospitals throughout the New York City metropolitan area and describe screening, clinical manifestations, EKG findings, imaging, and treatment.

resultsThe most common country of origin of our patients was El Salvador (n = 24, 40%), and the most common detection method was by routine blood donor screening (n = 21, 35%). Nearly half of the patients were asymptomatic (n = 29, 48%). Twenty-seven patients were treated with either benznidazole or nifurtimox, of whom 7 did not complete therapy due to side effects or were lost to follow-up. Ten patients had advanced heart failure requiring device implantation or organ transplantation.

conclusionsBased on our experience, we recommend that targeted screening be used to identify at-risk, asymptomatic patients before progression to clinical disease. Evaluation should include an electrocardiogram, echocardiogram, and chest x-ray, as well as gastrointestinal imaging if relevant symptoms are present. Patients should be treated if appropriate, but providers should be aware of adverse effects that may prevent patients from completing treatment.

Indexed as

Chagas diseaseheart transplantNew York Citynonendemic countriesTrypanosoma cruzi

Identifiers

PMID32500090
PMCPMC7255644
OpenAlexW3021207418

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.