ArticleFrontiers in bioengineering and biotechnology2020
Regional Nanoindentation Properties in Different Locations on the Mouse Tibia From C57BL/6 and Balb/C Female Mice.
Article in Frontiers in bioengineering and biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 12 citations in OpenAlex.
- Evaluating differences in Young's Modulus of regenerated and uninjured mouse digit bone through microCT density-based calculation and nanoindentation testing.Journal of biomechanics · 2022Article
- Loss of early B cell protein λ5 decreases bone mass and accelerates skeletal aging.Frontiers in immunology · 2022Article
- High bone mass phenotype in a cohort of patients with Osteogenesis Imperfecta caused due toBone reports · 2021Article
- Non-invasive prediction of the mouse tibia mechanical properties from microCT images: comparison between different finite element models.Biomechanics and modeling in mechanobiology · 2021Article
- Modeling Complex Orthopedic Trauma in Rodents: Bone, Muscle and Nerve Injury and Healing.Frontiers in pharmacology · 2020Review
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
Abstract
The local spatial heterogeneity of the material properties of the cortical and trabecular bone extracted from the mouse tibia is not well-known. Nevertheless, its characterization is fundamental to be able to study comprehensively the effect of interventions and to generate computational models to predict the bone strength preclinically. The goal of this study was to evaluate the nanoindentation properties of bone tissue extracted from two different mouse strains across the tibia length and in different sectors. Left tibiae were collected from four female mice, two C57BL/6, and two Balb/C mice. Nanoindentations with maximum 6 mN load were performed on different microstructures, regions along the axis of the tibiae, and sectors (379 in total). Reduced modulus (
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