Evidence map›Paper›PMID 32499911›Full record

ArticleMolecular and clinical oncology2020

Significance of bacterial and viral genotypes as a risk factor in driving cancer (Review).

Diwash Jangam, Alexandra Butzmann, Kaushik Sridhar, Stanley Deresinski, Niaz Banaei, Robert Shigeo Ohgami

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular and clinical oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Mutations inFrontiers in oncology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Diwash JangamDepartment of Pathology, Stanford University, Stanford, CA 94305, USA.
Alexandra ButzmannDepartment of Pathology, University of California San Francisco, San Francisco, CA 94143, USA.
Kaushik SridharDepartment of Pathology, University of California San Francisco, San Francisco, CA 94143, USA.
Stanley DeresinskiDepartment of Pathology, Stanford University, Stanford, CA 94305, USA.
Niaz BanaeiDepartment of Pathology, Stanford University, Stanford, CA 94305, USA.
Robert Shigeo OhgamiDepartment of Pathology, University of California San Francisco, San Francisco, CA 94143, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Microbes have been known to drive human cancers for over half a century. However, despite the association of bacterial and viral infections with a high risk of cancer, most infections do not result in the development of cancer. Additionally, certain bacteria and viruses, considered to drive oncogenesis, are commonly prevalent in the global population. The current study performed a comprehensive meta-analysis of primary literature data to identify particular aspects of microbial genotypes as crucial factors that dictate the cancer risks associated with infection. The results indicated the importance of incorporating microbial genotype information with human genotypes into clinical assays for the more efficient diagnosis and prognosis of patients with cancer. The current review focuses on the importance of microbial genotypes and specific genes and genetic differences that are important to human oncogenesis.

Indexed as

bacteriagenotypehuman cancerrisk factorvirus

Identifiers

PMID32499911
PMCPMC7265216

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.