Evidence map›Paper›PMID 32499849›Full record

ArticleThe Pan African medical journal2020

Characterisation of

Kapambwe Mwape, Geoffrey Kwenda, Annie Kalonda, John Mwaba, Chileshe Lukwesa-Musyani, Joseph Ngulube, Anthony Marius Smith, James Mwansa

Open access · goldAbstract readHistorical Article
In one paragraph

Article in The Pan African medical journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Dissecting serotype-specific contributions to live oral cholera vaccine efficacy.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Kapambwe MwapeDepartment of Basic Sciences, Michael Chilufya Sata School of Medicine, Copperbelt University, Ndola, Zambia.
Geoffrey KwendaDepartment of Biomedical Sciences, School of Health Sciences, University of Zambia, Lusaka, Zambia.
Annie KalondaDepartment of Biomedical Sciences, School of Health Sciences, University of Zambia, Lusaka, Zambia.
John MwabaDepartment of Biomedical Sciences, School of Health Sciences, University of Zambia, Lusaka, Zambia.
Chileshe Lukwesa-MusyaniDepartment of Pathology and Microbiology, University Teaching Hospital, Lusaka, Zambia.
Joseph NgulubeDepartment of Pathology and Microbiology, University Teaching Hospital, Lusaka, Zambia.
Anthony Marius SmithBacteriology Division, Centre for Enteric Diseases, National Institute for Communicable Diseases, National Health Laboratory Service, Johannesburg, South Africa.
James MwansaDepartment of Medical Microbiology, Faculty of Medicine, Lusaka Apex Medical University, Lusaka, Zambia.
University Teaching Hospital · ZMUniversity of Zambia · ZMCopperbelt University · ZMLusaka Apex Medical University · ZMNational Health Laboratory Service · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIn 2009 and 2010, more than 6,000 cholera cases were recorded during these outbreaks with more than 80% of cases recorded in Lusaka province. After a five-year break, in 2016 an outbreak occurred in Lusaka, causing more than 1,000 cases of cholera. This study will strengthen the epidemiological information on the changing characteristics of the cholera outbreaks, for treatment, prevention and control of the disease.

methodsThis was a laboratory-based descriptive cross-sectional study conducted at the University Teaching Hospital in Lusaka, Zambia. A total of 83

resultsMacrorestriction analysis of the isolates demonstrated high genetic diversity among the isolates with 16 different patterns. The largest pattern comprised 9 isolates while the smallest one had 1 isolate. 2009 and 2010 isolates were highly resistant to nalidixic acid and cotrimoxazole, but highly sensitive to azithromycin and ampicillin. Of the fifty-two isolates from the 2016 cholera outbreak, 90% (47) were sensitive to cotrimoxazole, 94% (49) to tetracycline, and 98% (51) to azithromycin, while 98% (51) were resistant to nalidixic acid and 31(60%) to ampicillin.

conclusionmacrorestriction analysis demonstrated high genetic diversity among the

Indexed as

AmpicillinAnti-Bacterial AgentsAzithromycinCholeraCross-Sectional StudiesDisease OutbreaksDrug Resistance, MultipleDrug Resistance, Multiple, BacterialElectrophoresis, Gel, Pulsed-FieldGenotypeHistory, 21st CenturyHospitals, TeachingHumansMicrobial Sensitivity TestsSerotypingVibrio cholerae O1AmpicillinAnti-Bacterial AgentsAzithromycinCholeraLusaka provincemultidrug resistanceVibrio cholerae

Identifiers

PMID32499849
PMCPMC7245973
OpenAlexW2978264336

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.