Evidence map›Paper›PMID 32499811›Full record

ArticleFrontiers in genetics2020

Dynamic Supraspliceosomes Are Assembled on Different Transcripts Regardless of Their Intron Number and Splicing State.

Naama Sebbag-Sznajder, Yehuda Brody, Hodaya Hochberg-Laufer, Yaron Shav-Tal, Joseph Sperling, Ruth Sperling

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Tethered Function Assays to Elucidate the Role of RNA-Binding Proteins.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Naama Sebbag-SznajderDepartment of Genetics, The Hebrew University of Jerusalem, Jerusalem, Israel.
Yehuda BrodyThe Mina and Everard Goodman Faculty of Life Sciences and The Institute of Nanotechnology and Advanced Materials, Bar Ilan University, Ramat Gan, Israel.
Hodaya Hochberg-LauferThe Mina and Everard Goodman Faculty of Life Sciences and The Institute of Nanotechnology and Advanced Materials, Bar Ilan University, Ramat Gan, Israel.
Yaron Shav-TalThe Mina and Everard Goodman Faculty of Life Sciences and The Institute of Nanotechnology and Advanced Materials, Bar Ilan University, Ramat Gan, Israel.
Joseph SperlingDepartment of Organic Chemistry, The Weizmann Institute of Science, Rehovot, Israel.
Ruth SperlingDepartment of Genetics, The Hebrew University of Jerusalem, Jerusalem, Israel.
Bar-Ilan University · ILHebrew University of Jerusalem · ILWeizmann Institute of Science · IL

Funding

The Mammalian Cellular Splicing Machine - Structure and FunctionR01GM079549 · NIGMS · HEBREW UNIVERSITY OF JERUSALEM · PI SPERLING, RUTH · 2008 to 2011
$836k
NIGMS NIH HHS R01 GM079549
6 · The paper itself

Abstract

Splicing and alternative splicing of pre-mRNA are key sources in the formation of diversity in the human proteome. These processes have a central role in the regulation of the gene expression pathway. Yet, how spliceosomes are assembled on a multi-intronic pre-mRNA is at present not well understood. To study the spliceosomes assembled

Indexed as

MS2-tagged supraspliceosomespre-mRNA splicingspecific supraspliceosomessplicing factorssplicing inhibition

Identifiers

PMID32499811
PMCPMC7243799
OpenAlexW3024385648

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.