Evidence map›Paper›PMID 32499767›Full record

ArticleFrontiers in microbiology2020

Improving HIV Outgrowth by Optimizing Cell-Culture Conditions and Supplementing With

Yuwei Zhang, Delphine Planas, Laurence Raymond Marchand, Marta Massanella, Huicheng Chen, Vanessa Sue Wacleche, Annie Gosselin, Jean-Philippe Goulet, Mario Filion, Jean-Pierre Routy and 2 more

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. HCV-specific CD4EBioMedicine · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Metformin Enhances Antibody-Mediated Recognition of HIV-Infected CD4bioRxiv : the preprint server for biology · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Flow Cytometry Sorting of Memory CCR6Methods in molecular biology (Clifton, N.J.) · 2022
    Article
  15. Th17 cell master transcription factor RORC2 regulates HIV-1 gene expression and viral outgrowth.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yuwei ZhangDépartement de microbiologie, infectiologie et immunologie, Faculté de Médecine, Université de Montréal, Montreal, QC, Canada.
Delphine PlanasDépartement de microbiologie, infectiologie et immunologie, Faculté de Médecine, Université de Montréal, Montreal, QC, Canada.
Laurence Raymond MarchandCentre hospitalier de l'Université de Montréal (CHUM)-Research Centre, Montreal, QC, Canada.
Marta MassanellaDépartement de microbiologie, infectiologie et immunologie, Faculté de Médecine, Université de Montréal, Montreal, QC, Canada.
Huicheng ChenDépartement de microbiologie, infectiologie et immunologie, Faculté de Médecine, Université de Montréal, Montreal, QC, Canada.
Vanessa Sue WaclecheDépartement de microbiologie, infectiologie et immunologie, Faculté de Médecine, Université de Montréal, Montreal, QC, Canada.
Annie GosselinCentre hospitalier de l'Université de Montréal (CHUM)-Research Centre, Montreal, QC, Canada.
Jean-Philippe GouletCaprion, Montreal, QC, Canada.
Mario FilionAlethia Biotherapeutics, Montreal, QC, Canada.
Jean-Pierre RoutyMcGill University Health Centre, Montreal, QC, Canada.
Nicolas ChomontDépartement de microbiologie, infectiologie et immunologie, Faculté de Médecine, Université de Montréal, Montreal, QC, Canada.
Petronela AncutaDépartement de microbiologie, infectiologie et immunologie, Faculté de Médecine, Université de Montréal, Montreal, QC, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The persistence of replication-competent HIV reservoirs in people living with HIV (PLWH) receiving antiretroviral therapy (ART) is a barrier to cure. Therefore, their accurate quantification is essential for evaluating the efficacy of new therapeutic interventions and orienting the decision to interrupt ART. Quantitative viral outgrowth assays (QVOAs) represent the "

Indexed as

ARTATRAHIV-1 reservoirsmemory CD4+ T-cellsQVOAs

Identifiers

PMID32499767
PMCPMC7243435

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.