ArticleFrontiers in physiology2020
Poor Embryo Quality Is Associated With A Higher Risk of Low Birthweight in Vitrified-Warmed Single Embryo Transfer Cycles.
Article in Frontiers in physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Effect of blastocyst quality on neonatal outcomes in frozen embryo transfer cycles: a cohort study.Journal of assisted reproduction and genetics · 2025Article
- Blastocyst quality and congenital malformation risk in singleton births after frozen embryo transfer.Scientific reports · 2025Article
- Factors influencing the birth weight of ART-conceived offspring.Journal of assisted reproduction and genetics · 2025Review
- Embryo Transfer Procedural Parameters Do Not Predict IVF Cycle Outcome.Journal of clinical medicine · 2024Article
- Influencing factors and predictive model of live birth involving low-grade blastocyst frozen-thawed transfer: a retrospective study.European journal of medical research · 2023Article
- Trophectoderm biopsy is associated with adverse obstetric outcomes rather than neonatal outcomes.BMC pregnancy and childbirth · 2023Article
- The effect of transferring a poor-quality embryo together with a good-quality embryo on the singleton birth weight: A retrospective cohort study.International journal of reproductive biomedicine · 2022Article
- Blastocyst quality and perinatal outcomes of frozen-thawed single blastocyst transfer cycles.Frontiers in endocrinology · 2022Article
- Day-3-embryo fragmentation is associated with singleton birth weight following fresh single blastocyst transfer: A retrospective study.Frontiers in endocrinology · 2022Article
- Blastocyst quality and perinatal outcomes in women undergoing single blastocyst transfer in frozen cycles.Human reproduction open · 2021Article
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7 authors.
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Abstract
backgroundPrevious studies have reported the association between embryo quality and perinatal outcomes in fresh cycles, after cleavage-stage or blastocyst embryo transfer, and found no significant difference. However, in terms of vitrified-warmed embryo transfer cycles, the impact of embryo quality on neonatal and maternal outcomes has not been evaluated.
objectivesTo explore the association between the quality of a single vitrified-warmed embryo and perinatal outcomes.
methodsThis retrospective study included 2403 live-born singletons derived from single vitrified-warmed embryo transfer cycles during January 2006 and July 2018. Neonatal and maternal outcomes were compared between singletons resulting from the use of single good quality embryo (GQE) (
resultsA significantly higher risk of low birthweight (LBW, birthweight <2500 g) was observed in the singletons derived from the transfer of single PQE compared with those derived from the transfer of single GQE both in cleavage and blastocyst stages (cleavage-stage, AOR 2.62, 95% CI 1.27-5.37; blastocyst stage, AOR 1.98, 95% CI 1.06-3.70). An increased risk of preterm birth (PTB, gestational age <37 weeks) was also observed in singletons born after transfer of a PQE of cleavage-stage compared with those after a GQE of cleavage-stage (AOR 2.40, 95% CI 1.28-4.49). The transfer of single poor quality blastocyst was associated with a higher risk of placenta previa compared with the transfer of single good quality blastocyst (AOR 2.65, 95% CI 1.26-5.57). Other maternal complications, neonatal malformations, and neonatal complications were similar between compared groups.
conclusionIn vitrified-warmed cycles with single embryo transfer, poor embryo quality would result in a significantly higher risk of LBW, regardless of cleavage-stage or blastocyst embryo transfer. Meanwhile, the transfer of poor cleavage-stage embryo was also associated with an increased incidence of PTB.
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