ArticleScientific reports2020
Short microsecond pulses achieve homogeneous electroporation of elongated biological cells irrespective of their orientation in electric field.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- Resolving nanosecond kinetics of the optical membrane potential in pulsed electric fields.Bioelectrochemistry (Amsterdam, Netherlands) · 2026Article
- Lesion Formation in Cardiac Pulsed-Field Ablation: Acute to Chronic Cellular Level Changes.Pacing and clinical electrophysiology : PACE · 2026Review
- Atrial fibrillation and flutter conversion with pulsed electric field delivery: preclinical proof of concept.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2025Article
- Pulsed Field Ablation: A Comprehensive Update.Journal of clinical medicine · 2024Review
- Genetically engineered HEK cells as a valuable tool for studying electroporation in excitable cells.Scientific reports · 2024Article
- Pulsed Field Ablation for the Treatment of Atrial Fibrillation: A Review and a Look into its Future.The heart surgery forum · 2024Article
- Pearls and Pitfalls of Pulsed Field Ablation.Korean circulation journal · 2023Review
- Article
- Pulsed Electric Field Ablation of Esophageal Malignancies and Mitigating Damage to Smooth Muscle: An In Vitro Study.International journal of molecular sciences · 2023Article
- Determination of lethal electric field threshold for pulsed field ablation inFrontiers in cardiovascular medicine · 2023Article
- Reversible and Irreversible Effects of Electroporation on Contractility and Calcium Homeostasis in Isolated Cardiac Ventricular Myocytes.Circulation. Arrhythmia and electrophysiology · 2022Article
- Pulsed Electric Fields Alter Expression of NF-κB Promoter-Controlled Gene.International journal of molecular sciences · 2021Article
- Pulse Duration Dependent Asymmetry in Molecular Transmembrane Transport Due to Electroporation in H9c2 Rat Cardiac Myoblast Cells In Vitro.Molecules (Basel, Switzerland) · 2021Article
- Proximity-induced electrodeformation and membrane capacitance coupling between cells.European biophysics journal : EBJ · 2021Article
- Study on Optimal Parameter and Target for Pulsed-Field Ablation of Atrial Fibrillation.Frontiers in cardiovascular medicine · 2021Article
- Recent advances in critical nodes of embryo engineering technology.Theranostics · 2021Review
- A Novel Electroporation System for Living Cell Staining and Membrane Dynamics Interrogation.Micromachines · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In gene electrotransfer and cardiac ablation with irreversible electroporation, treated muscle cells are typically of elongated shape and their orientation may vary. Orientation of cells in electric field has been reported to affect electroporation, and hence electrodes placement and pulse parameters choice in treatments for achieving homogeneous effect in tissue is important. We investigated how cell orientation influences electroporation with respect to different pulse durations (ns to ms range), both experimentally and numerically. Experimentally detected electroporation (evaluated separately for cells parallel and perpendicular to electric field) via Ca
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.