Evidence map›Paper›PMID 32499556›Full record

ReviewThe Journal of antibiotics2020

Role of symbiosis in the discovery of novel antibiotics.

Vedanjali Gogineni, Xiaoyan Chen, George Hanna, Dian Mayasari, Mark T Hamann

Abstract readReview
In one paragraph

Review in The Journal of antibiotics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. The Metabolite Profiling ofMetabolites · 2023
    Article
  7. Modern Trends in Natural Antibiotic Discovery.Life (Basel, Switzerland) · 2023
    Review
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Vedanjali GogineniAnalytical Development Department, Cambrex Pharmaceuticals, Charles City, IA, USA.ORCID http://orcid.org/0000-0002-2506-7434
Xiaoyan ChenDepartment of Drug Discovery, Biomedical Sciences and Public Health, College of Pharmacy and Medicine, Medical University of South Carolina, Charleston, SC, USA.
George HannaDepartment of Drug Discovery, Biomedical Sciences and Public Health, College of Pharmacy and Medicine, Medical University of South Carolina, Charleston, SC, USA.
Dian MayasariDepartment of Pharmaceutical Biology, Faculty of Pharmacy, University of Gadjah Mada, Yogyakarta, Indonesia.
Mark T HamannDepartment of Drug Discovery, Biomedical Sciences and Public Health, College of Pharmacy and Medicine, Medical University of South Carolina, Charleston, SC, USA. hamannm@musc.edu.ORCID http://orcid.org/0000-0002-3798-4002

Funding

Natural Product HCV Drugs from Rare Plant-Microbe InteractionsR01AT007318 · NCCIH · UNIVERSITY OF MISSISSIPPI · PI HAMANN, MARK T · 2012 to 2016
$1.6M
Complimentary NMR and Bio-Assay Guided Screening of Edible Marine Algae for AGE Inhibitors to Control Glycative Stress and Reduce Risk of Neurodegeneration.F31AT011158 · NCCIH · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI HANNA, GEORGE STEVEN · 2020 to 2022
$132k
NCCIH NIH HHS F31 AT011158NCCIH NIH HHS R01 AT007318
6 · The paper itself

Abstract

Antibiotic resistance has been an ongoing challenge that has emerged almost immediately after the initial discovery of antibiotics and requires the development of innovative new antibiotics and antibiotic combinations that can effectively mitigate the development of resistance. More than 35,000 people die each year from antibiotic resistant infections in just the United States. This signifies the importance of identifying other alternatives to antibiotics for which resistance has developed. Virtually, all currently used antibiotics can trace their genesis to soil derived bacteria and fungi. The bacteria and fungi involved in symbiosis is an area that still remains widely unexplored for the discovery and development of new antibiotics. This brief review focuses on the challenges and opportunities in the application of symbiotic microbes and also provides an interesting platform that links natural product chemistry with evolutionary biology and ecology.

Indexed as

AnimalsAnti-Bacterial AgentsBacteriaBiological ProductsDrug Resistance, MicrobialFungiHumansSymbiosisUnited StatesAnti-Bacterial AgentsBiological Products

Identifiers

PMID32499556
PMCPMC12570216

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.