ArticleScientific reports2020
Sleep disturbance-related depressive symptom and brain volume reduction in shift-working nurses.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 37 citations in OpenAlex.
- Latent Class Analysis of Shift Work Patterns Among Nurses and Its Impact on Anxiety-Depression Comorbidity: A Multicenter Cross-Sectional Study.Depression and anxiety · 2026Article
- Association Between Shift Working and Brain Morphometric Changes in Workers: A Voxel-wise Comparison.Safety and health at work · 2025Article
- Article
- Long-term night-shift work is associated with accelerates brain aging and worsens N3 sleep in female nurses.Sleep medicine · 2024Article
- [Insomniac symptoms and suicidality-link and management].Neuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Osterreichischer Nervenarzte und Psychiater · 2024Review
- Sleep disturbance and internalizing symptoms in adolescents: a moderated mediation model of self-control and mindfulness.BMC psychiatry · 2024Article
- Alterations of functional brain activity and connectivity in female nurses working on long-term shift.Nursing open · 2024Article
- Cerebral blood flow in the paracentral lobule is associated with poor subjective sleep quality among patients with a history of methadone maintenance treatment.Frontiers in neurology · 2024Article
- Brain structural correlates of subjective sleepiness and insomnia symptoms in shift workers.Frontiers in neuroscience · 2024Article
- Identifying major depressive disorder with associated sleep disturbances through fMRI regional homogeneity at rest.BMC psychiatry · 2023Article
- Risk prediction of sleep disturbance in clinical nurses: a nomogram and artificial neural network model.BMC nursing · 2023Article
- The Relationship between Working Night Shifts and Depression among Nurses: A Systematic Review and Meta-Analysis.Healthcare (Basel, Switzerland) · 2023Review
- Keep Your Mask On: The Benefits of Masking for Behavior and the Contributions of Aging and Disease on Dysfunctional Masking Pathways.Frontiers in neuroscience · 2022Review
- Association of industrial work schedules with development of metabolic syndrome, insulin resistance, and serum adipokine concentrations.Asian biomedicine : research, reviews and news · 2021Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Disturbed sleep is the most common effect of shift work. A large corpus of research indicates an association between sleep disturbance and depressive symptom in shift workers. In this study, we proposed the mediating role of grey matter (GM) structure in the relationship between sleep disturbance and depressive symptom. We collected structural MRI (sMRI) data as well as assessing the level of sleep disturbance and depressive symptom with the Pittsburgh Sleep disturbance Index and Zung Self-Rating Depression Scale, respectively, in 20 shift-working nurses and 19 day-working nurses. The shift-working nurses reported greater severity of sleep disturbance and depressive symptom, and furthermore, they exhibited reduced GM volume in the left postcentral gyrus (PostCG), right PostCG, right paracentral lobule, and left superior temporal gyrus (STG), compared to the day-working nurses. For each of the four brain regions, we formulated a mediation hypothesis by developing a mediation model that represents a causal chain between GM volume, sleep disturbance, and depressive symptom. Tests of the hypothesis on the mediation of GM volume revealed that inter-individual variations in left PostCG volume and left STG volume accounted for the influence of sleep disturbance on depressive symptom. These results suggest that structural alterations in PostCG and STG play an intervening role in the development of depressive symptom following sleep disturbance. We propose the need of considering neuroanatomical abnormalities in explaining and understanding symptomatic changes induced by sleep disturbance.
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