ArticleScientific reports2020
Spectral and spatial shaping of laser-driven proton beams using a pulsed high-field magnet beamline.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 3 citations in OpenAlex.
- Stable laser-acceleration of high-flux proton beams with plasma collimation.Nature communications · 2025Article
- Design and implementation of the first proton beam transport line in VEGA-3 Petawatt laser system.Scientific reports · 2024Article
- The DRESDEN PLATFORM is a research hub for ultra-high dose rate radiobiology.Scientific reports · 2023Article
- Transformative Technology for FLASH Radiation Therapy.Applied sciences (Basel, Switzerland) · 2023Article
- Time-of-flight spectroscopy for laser-driven proton beam monitoring.Scientific reports · 2022Article
- Low divergent MeV-class proton beam with micrometer source size driven by a few-cycle laser pulse.Scientific reports · 2022Article
- Angular-Resolved Thomson Parabola Spectrometer for Laser-Driven Ion Accelerators.Sensors (Basel, Switzerland) · 2022Article
- A new platform for ultra-high dose rate radiobiological research using the BELLA PW laser proton beamline.Scientific reports · 2022Article
- Geant4 Monte Carlo simulation study of the secondary radiation fields at the laser-driven ion source LION.Scientific reports · 2021Article
- Review
- First on-line detection of radioactive fission isotopes produced by laser-accelerated protons.Scientific reports · 2020Article
Corrections and comments
- Erratum issued
Authors and funding
20 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Intense laser-driven proton pulses, inherently broadband and highly divergent, pose a challenge to established beamline concepts on the path to application-adapted irradiation field formation, particularly for 3D. Here we experimentally show the successful implementation of a highly efficient (50% transmission) and tuneable dual pulsed solenoid setup to generate a homogeneous (laterally and in depth) volumetric dose distribution (cylindrical volume of 5 mm diameter and depth) at a single pulse dose of 0.7 Gy via multi-energy slice selection from the broad input spectrum. The experiments were conducted at the Petawatt beam of the Dresden Laser Acceleration Source Draco and were aided by a predictive simulation model verified by proton transport studies. With the characterised beamline we investigated manipulation and matching of lateral and depth dose profiles to various desired applications and targets. Using an adapted dose profile, we performed a first proof-of-technical-concept laser-driven proton irradiation of volumetric in-vitro tumour tissue (SAS spheroids) to demonstrate concurrent operation of laser accelerator, beam shaping, dosimetry and irradiation procedure of volumetric biological samples.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.