ArticleGut2021
Prediction model of bleeding after endoscopic submucosal dissection for early gastric cancer: BEST-J score.
Article in Gut, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 99 papers, 3 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
99 citing papers in PubMed, 3 syntheses or guidelines pooled it, 152 citations in OpenAlex.
- Risk Prediction Models for Delayed Bleeding After Endoscopic Submucosal Dissection in Patients with Early Gastric Cancer: A Systematic Review and Meta-Analysis.Journal of gastrointestinal cancer · 2026Pooled it
- Comparison of vonoprazan and proton pump inhibitors for the management of gastric post-endoscopic submucosal dissection ulcers and preventing delayed bleeding: a meta-analysis of randomized controlled trials.Frontiers in medicine · 2026Pooled it
- Potential of Direct Oral Anticoagulant in Bleeding After Gastric Endoscopic Submucosal Dissection: A Systematic Review and Meta-Analysis.Digestive diseases and sciences · 2024Pooled it
- Perioperative multidisciplinary nursing model for endoscopic gastric submucosal dissection development and effect evaluation.World journal of gastrointestinal surgery · 2026Trial
- Vonoprazan or Proton Pump Inhibitor for Gastric Endoscopic Submucosal Dissection in Patients Taking Antithrombotic Agents.Journal of gastroenterology and hepatology · 2025Trial
- Endoscopic Closure Utilizing Endoloop and Endoclips After Gastric Endoscopic Submucosal Dissection for Patients on Antithrombotic Therapy.Digestive diseases and sciences · 2021Trial
- Through-the-scope twin clip for closure of gastric endoscopic full-thickness resection defects: a retrospective comparative study.Annals of medicine · 2026Article
- Endoscopic Hand Suturing After Gastric Endoscopic Submucosal Dissection in Patients with Low to Intermediate Risk of Delayed Bleeding: A Retrospective Pilot Study.Digestive diseases and sciences · 2026Observational
- A preoperative risk-scoring model for predicting intraoperative hemorrhage during endoscopic submucosal dissection for gastric neoplasms.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2026Article
- The Hedgehog Method Following Gastric Endoscopic Submucosal Dissection: Observed Postoperative Bleeding Rates Across BEST-J Risk Categories.Digestive diseases and sciences · 2026Article
- A pilot study on the efficacy of cyanoacrylate glue in preventing post-ESD bleeding at the gastric angle.Surgical endoscopy · 2026Article
- Takotsubo syndrome following delayed bleeding after gastric endoscopic submucosal dissection: a case report.Clinical journal of gastroenterology · 2026Article
- Feasibility of Zeosuture M for gastric endoscopic submucosal dissection defect closure during anticoagulation: a preclinical porcine study from Japan.Clinical endoscopy · 2026Article
- Risk of Postoperative Bleeding in Esophageal Endoscopic Submucosal Dissection for Squamous Cell Carcinoma in Patients on Antiplatelet Therapy: A Multicenter Retrospective Study in Japan.Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society · 2026Article
- Effect of Oral Proton-Pump Inhibitor Administration on Reducing the Delayed Bleeding Risk in 5 Upper Gastrointestinal Endoscopic Treatments.The American journal of gastroenterology · 2026Article
- Establishment and validation of a predictive scoring system for titanium clip retention at six months after endoscopic submucosal dissection for gastric lesions.Scientific reports · 2026Article
- Reopenable clip-over-the-line method with endoloop anchoring for gastric defect closure after endoscopic submucosal dissection.Endoscopy · 2026Article
- Prediction of delayed bleeding after endoscopic submucosal dissection in early gastric cancer and precancerous lesions by BEST-C score.Surgical endoscopy · 2026Article
- Ilaprazole Versus Esomeprazole for Artificial Ulcer Healing After Gastric Endoscopic Submucosal Dissection: A Single-Center Retrospective Study.Journal of clinical medicine · 2026Article
- Article
39 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
38 authors at 20 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveBleeding after endoscopic submucosal dissection (ESD) for early gastric cancer (EGC) is a frequent adverse event after ESD. We aimed to develop and externally validate a clinically useful prediction model (BEST-J score: Bleeding after ESD Trend from Japan) for bleeding after ESD for EGC.
designThis retrospective study enrolled patients who underwent ESD for EGC. Patients in the derivation cohort (n=8291) were recruited from 25 institutions, and patients in the external validation cohort (n=2029) were recruited from eight institutions in other areas. In the derivation cohort, weighted points were assigned to predictors of bleeding determined in the multivariate logistic regression analysis and a prediction model was established. External validation of the model was conducted to analyse discrimination and calibration.
resultsA prediction model comprised 10 variables (warfarin, direct oral anticoagulant, chronic kidney disease with haemodialysis, P2Y12 receptor antagonist, aspirin, cilostazol, tumour size >30 mm, lower-third in tumour location, presence of multiple tumours and interruption of each kind of antithrombotic agents). The rates of bleeding after ESD at low-risk (0 to 1 points), intermediate-risk (2 points), high-risk (3 to 4 points) and very high-risk (≥5 points) were 2.8%, 6.1%, 11.4% and 29.7%, respectively. In the external validation cohort, the model showed moderately good discrimination, with a
conclusionsIn this nationwide multicentre study, we derived and externally validated a prediction model for bleeding after ESD. This model may be a good clinical decision-making support tool for ESD in patients with EGC.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.