Evidence map›Paper›PMID 32499377›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2020

Modular and Distinct Plexin-A4/FARP2/Rac1 Signaling Controls Dendrite Morphogenesis.

Victor Danelon, Ron Goldner, Edward Martinez, Irena Gokhman, Kimberly Wang, Avraham Yaron, Tracy S Tran

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
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  6. PAK1 inhibitor NVS-PAK1-1 preserves dendritic spines in amyloid/tau exposed neurons and 5xFAD mice.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
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  7. Review
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  16. Semaphorin signaling restricts neuronal regeneration inFrontiers in cell and developmental biology · 2022
    Article
  17. Article
  18. Article
  19. Review
  20. Semaphorins in Adult Nervous System Plasticity and Disease.Frontiers in synaptic neuroscience · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Victor DanelonDepartment of Biological Sciences, Rutgers University, Newark, New Jersey 07102.
Ron GoldnerDepartment of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, 76100, Israel.
Edward MartinezDepartment of Biological Sciences, Rutgers University, Newark, New Jersey 07102.
Irena GokhmanDepartment of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, 76100, Israel.
Kimberly WangDepartment of Biological Sciences, Rutgers University, Newark, New Jersey 07102.
Avraham YaronDepartment of Biomolecular Sciences, Weizmann Institute of Science, Rehovot, 76100, Israel tstran@rutgers.edu avraham.yaron@weizmann.ac.il.
Tracy S TranDepartment of Biological Sciences, Rutgers University, Newark, New Jersey 07102 tstran@rutgers.edu avraham.yaron@weizmann.ac.il.ORCID 0000-0002-2179-5725
Rutgers, The State University of New Jersey · USWeizmann Institute of Science · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diverse neuronal populations with distinct cellular morphologies coordinate the complex function of the nervous system. Establishment of distinct neuronal morphologies critically depends on signaling pathways that control axonal and dendritic development. The Sema3A-Nrp1/PlxnA4 signaling pathway promotes cortical neuron basal dendrite arborization but also repels axons. However, the downstream signaling components underlying these disparate functions of Sema3A signaling are unclear. Using the novel

Indexed as

Adaptor Proteins, Signal TransducingAnimalsAxonsCells, CulturedDendritesFemaleGuanine Nucleotide Exchange FactorsMaleMiceMice, KnockoutNerve Tissue ProteinsNeuronal PlasticityNeuronsNeuropeptidesrac1 GTP-Binding ProteinReceptors, Cell SurfaceAdaptor Proteins, Signal TransducingFARP2 protein, mouseGuanine Nucleotide Exchange FactorsNerve Tissue ProteinsNeuropeptidesPlxna4 protein, mouserac1 GTP-Binding ProteinRac1 protein, mouseReceptors, Cell SurfaceSema3a protein, mouseSemaphorin-3Aaxonal repulsiondendritic branchingguidance receptorsneural developmentSemaphorin signaling

Identifiers

PMID32499377
PMCPMC7343331
OpenAlexW3033771771

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.