Evidence map›Paper›PMID 32499373›Full record

ArticleThe Journal of biological chemistry2020

FACS-array-based cell purification yields a specific transcriptome of striatal medium spiny neurons in a murine Huntington disease model.

Haruko Miyazaki, Tomoyuki Yamanaka, Fumitaka Oyama, Yoshihiro Kino, Masaru Kurosawa, Mizuki Yamada-Kurosawa, Risa Yamano, Tomomi Shimogori, Nobutaka Hattori, Nobuyuki Nukina

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. The role(s) of NF-Y in development and differentiation.Cell death and differentiation · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Non-Cell Autonomous and Epigenetic Mechanisms of Huntington's Disease.International journal of molecular sciences · 2021
    Review
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Haruko MiyazakiLaboratory of Structural Neuropathology, Graduate School of Brain Science, Doshisha University, Kyoto, Japan.
Tomoyuki YamanakaLaboratory of Structural Neuropathology, Graduate School of Brain Science, Doshisha University, Kyoto, Japan.ORCID 0000-0002-5378-4326
Fumitaka OyamaLaboratory for Structural Neuropathology, RIKEN Brain Science Institute, Saitama, Japan.
Yoshihiro KinoLaboratory for Structural Neuropathology, RIKEN Brain Science Institute, Saitama, Japan.ORCID 0000-0003-0862-8065
Masaru KurosawaLaboratory for Structural Neuropathology, RIKEN Brain Science Institute, Saitama, Japan.
Mizuki Yamada-KurosawaLaboratory for Structural Neuropathology, RIKEN Brain Science Institute, Saitama, Japan.
Risa YamanoLaboratory of Structural Neuropathology, Graduate School of Brain Science, Doshisha University, Kyoto, Japan.
Tomomi ShimogoriLaboratory for Molecular Mechanisms of Brain Development, RIKEN Center for Brain Science, Saitama, Japan.
Nobutaka HattoriDepartment of Neurology, Juntendo University Graduate School of Medicine, Tokyo, Japan.ORCID 0000-0002-2034-2556
Nobuyuki NukinaLaboratory of Structural Neuropathology, Graduate School of Brain Science, Doshisha University, Kyoto, Japan nnukina@mail.doshisha.ac.jp.ORCID 0000-0002-4545-5100
Doshisha University · JPRIKEN Center for Brain Science · JPJuntendo University · JPKogakuin University · JPMeiji Pharmaceutical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Huntington disease (HD) is a neurodegenerative disorder caused by expanded CAG repeats in the

Indexed as

Flow CytometryTranscriptomeAnimalsCorpus StriatumDisease Models, AnimalHuntingtin ProteinHuntington DiseaseMaleMiceMice, TransgenicHtt protein, mouseHuntingtin ProteinDNA damagefluorescence-activated cell sorting (FACS)Huntington diseasemedium spiny neuron (MSN)microarrayneurodegenerationR6/2 mouse modelstriatumtranscription regulationtranscriptomics

Identifiers

PMID32499373
PMCPMC7380199
OpenAlexW3033574098

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.