Evidence map›Paper›PMID 32499306›Full record

SynthesisEuropean respiratory review : an official journal of the European Respiratory Society2020

Risk factors for all-cause hospital readmission following exacerbation of COPD: a systematic review and meta-analysis.

Jaber S Alqahtani, Chidiamara M Njoku, Bonnie Bereznicki, Barbara C Wimmer, Gregory M Peterson, Leigh Kinsman, Yousef S Aldabayan, Ahmed M Alrajeh, Abdulelah M Aldhahir, Swapna Mandal and 1 more

Open access · diamondAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in European respiratory review : an official journal of the European Respiratory Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 97 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
97citing papers in PubMed, 10 pooled it
12.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

97 citing papers in PubMed, 10 syntheses or guidelines pooled it, 140 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Pooled it
  10. Pooled it
  11. Trial
  12. Trial
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Integration of the Clinical Pharmacist Practitioner to Improve Rural Veteran Access and Quality for Chronic Obstructive Pulmonary Disease in Primary Care.The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association · 2026
    Article
  20. Article

37 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 3 countries.

Jaber S AlqahtaniUCL Respiratory, University College London, London, UK Alqahtani-Jaber@hotmail.com.ORCID https://orcid.org/0000-0003-1795-5092
Chidiamara M NjokuSchool of Medicine, College of Health and Medicine, University of Tasmania, Hobart, Australia.
Bonnie BereznickiSchool of Medicine, College of Health and Medicine, University of Tasmania, Hobart, Australia.
Barbara C WimmerSchool of Medicine, College of Health and Medicine, University of Tasmania, Hobart, Australia.
Gregory M PetersonSchool of Medicine, College of Health and Medicine, University of Tasmania, Hobart, Australia.
Leigh KinsmanSchool of Nursing and Midwifery, University of Newcastle, Port Macquarie, Australia.
Yousef S AldabayanUCL Respiratory, University College London, London, UK.
Ahmed M AlrajehUCL Respiratory, University College London, London, UK.ORCID https://orcid.org/0000-0003-2559-416X
Abdulelah M AldhahirUCL Respiratory, University College London, London, UK.ORCID https://orcid.org/0000-0002-4270-9494
Swapna MandalUCL Respiratory, University College London, London, UK.
John R HurstUCL Respiratory, University College London, London, UK.ORCID https://orcid.org/0000-0002-7246-6040
University College London · GBUniversity of Tasmania · AUMacquarie University · AURoyal Free London NHS Foundation Trust · GBThe London College · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundReadmission rates following hospitalisation for COPD exacerbations are unacceptably high, and the contributing factors are poorly understood. Our objective was to summarise and evaluate the factors associated with 30- and 90-day all-cause readmission following hospitalisation for an exacerbation of COPD.

methodsWe systematically searched electronic databases from inception to 5 November 2019. Data were extracted by two independent authors in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Study quality was assessed using a modified version of the Newcastle-Ottawa Scale. We synthesised a narrative from eligible studies and conducted a meta-analysis where this was possible using a random-effects model.

resultsIn total, 3533 abstracts were screened and 208 full-text manuscripts were reviewed. A total of 32 papers met the inclusion criteria, and 14 studies were included in the meta-analysis. The readmission rate ranged from 8.8-26.0% at 30 days and from 17.5-39.0% at 90 days. Our narrative synthesis showed that comorbidities, previous exacerbations and hospitalisations, and increased length of initial hospital stay were the major risk factors for readmission at 30 and 90 days. Pooled adjusted odds ratios (95% confidence intervals) revealed that heart failure (1.29 (1.22-1.37)), renal failure (1.26 (1.19-1.33)), depression (1.19 (1.05-1.34)) and alcohol use (1.11 (1.07-1.16)) were all associated with an increased risk of 30-day all-cause readmission, whereas being female was a protective factor (0.91 (0.88-0.94)).

conclusionsComorbidities, previous exacerbations and hospitalisation, and increased length of stay were significant risk factors for 30- and 90-day all-cause readmission after an index hospitalisation with an exacerbation of COPD.

Indexed as

Patient ReadmissionAdultAgedAged, 80 and overComorbidityDisease ProgressionFemaleHumansLength of StayMaleMiddle AgedPrognosisPulmonary Disease, Chronic ObstructiveRisk AssessmentRisk FactorsTime Factors

Identifiers

PMID32499306
PMCPMC9488450
OpenAlexW3033975634

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.