Evidence map›Paper›PMID 32499257›Full record

Trial reportBMJ open2020

Sociodemographic predictors of early postnatal growth: evidence from a Chilean infancy cohort.

Ann Von Holle, Kari E North, Sheila Gahagan, Raquel A Burrows, Estela Blanco, Betsy Lozoff, Annie Green Howard, Anne Justice, Misa Graff, Venkata Saroja Voruganti

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in BMJ open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ann Von HolleDepartment of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA avonholle@gmail.com.ORCID 0000-0002-0299-1114
Kari E NorthDepartment of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Sheila GahaganDivision of Child Development and Community Health, University of California San Diego, La Jolla, California, USA.ORCID 0000-0002-1105-7323
Raquel A BurrowsInstitute of Nutrition and Food Technology, University of Chile, Santiago, Chile.
Estela BlancoDivision of Child Development and Community Health, University of California San Diego, La Jolla, California, USA.
Betsy LozoffDepartment of Pediatrics, University of Michigan, Ann Arbor, Michigan, USA.
Annie Green HowardDepartment of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Anne JusticeCenter for Biomedical and Translational Informatics, Geisinger Health, Danville, Pennsylvania, USA.
Misa GraffDepartment of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Venkata Saroja VorugantiDepartment of Nutrition and UNC Nutrition Research Institute, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.

Funding

Research Services CoreP2CHD050924 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KAREN B GUZZO · 2015 to 2026
$9.6M
NEUROMATURATION DELAYS IN IRON DEFICIENT ANEMIC INFANTSR01HD033487 · NICHD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI GAHAGAN, SHEILA, LOZOFF, BETSY · 1997 to 2016
$8.8M
Biopsychosocial Determinants of Adolescent Obesity/Cardiovascular RiskR01HL088530 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI GAHAGAN, SHEILA · 2008 to 2017
$5.0M
NHLBI NIH HHS R01 HL088530NICHD NIH HHS R01 HD033487
6 · The paper itself

Abstract

objectivesInfant anthropometric growth varies across socioeconomic factors, including maternal education and income, and may serve as an indicator of environmental influences in early life with long-term health consequences. Previous research has identified sociodemographic gradients in growth with a focus on the first year and beyond, but estimates are sparse for growth before 6 months. Thus, our objective was to examine the relationship between sociodemographic factors and infant growth patterns between birth and 5 months of age.

designProspective cohort study. SETTINGS: Low-income to middle-income neighbourhoods in Santiago, Chile (1991-1996).

participants1412 participants from a randomised iron-deficiency anaemia preventive trial in healthy infants.

main outcome measuresLongitudinal anthropometrics including monthly weight (kg), length (cm) and weight-for-length (WFL) values. For each measure, we estimated three individual-level growth parameters (size, timing and velocity) from SuperImposition by Translation and Rotation models. Size and timing changes represent vertical and horizontal growth curve shifts, respectively, and velocity change represents growth rate shifts. We estimated the linear association between growth parameters and gestational age, maternal age, education and socioeconomic position (SEP).

resultsLower SEP was associated with a slower linear (length) velocity growth parameter (-0.22, 95% CI -0.31 to -0.13)-outcome units are per cent change in velocity from the average growth curve. Lower SEP was associated with later WFL growth timing as demonstrated through the tempo growth parameter for females (0.25, 95% CI 0.05 to 0.42)-outcome units are shifts in days from the average growth curve. We found no evidence of associations between SEP and the weight size, timing or velocity growth rate parameters.

conclusionPrevious research on growth in older infants and children shows associations between lower SEP with slower length velocity. We found evidence supporting this association in the first 5 months of life, which may inform age-specific prevention efforts aimed at infant length growth.

Indexed as

Child DevelopmentSocioeconomic FactorsAnemia, Iron-DeficiencyAnthropometryChileFemaleHumansInfantInfant, NewbornMalePoverty AreasProspective Studiescommunity child healthepidemiologypublic health

Identifiers

PMID32499257
PMCPMC7282289

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.