ArticleHealth and quality of life outcomes2020
Quality of life up to 10 years after traumatic brain injury: a cross-sectional analysis.
Article in Health and quality of life outcomes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
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Who cites it
37 citing papers in PubMed, 65 citations in OpenAlex.
- Early post-hospital trajectories of health-related quality of life for younger adult patients with traumatic brain injury.Archives of physical medicine and rehabilitation · 2026Article
- Research progress on biomarkers of traumatic brain injury.Animal models and experimental medicine · 2026Review
- Neurostimulant Use and Cognitive Outcomes in Patients with Acute, Severe Traumatic Brain Injury.Neurocritical care · 2026Article
- Machine-learning algorithms for detecting intracranial hemorrhage on head computed tomography.The Cochrane database of systematic reviews · 2026Article
- Assessment of quality of life after traumatic brain injury in adults from Armenia, Georgia, and Moldova using EQ-5D-5L.Scientific reports · 2025Article
- The border-associated macrophage marker MRC1 contributes to an early neuroprotective inflammatory response to traumatic brain injury in mice.Acta neuropathologica communications · 2025Article
- One-Year Outcomes After Traumatic Brain Injury and Early Extracranial Surgery in the TRACK-TBI Study.JAMA network open · 2025Observational
- The relationship between personality traits and health-related quality of life after mild-to-moderate traumatic brain injury.BMC neurology · 2025Article
- The role of isolated diffuse axonal brain injury on post-traumatic depressive- and anxiety-like behavior in rats.Translational psychiatry · 2025Article
- Intranasal delivery of engineered extracellular vesicles promotes neurofunctional recovery in traumatic brain injury.Journal of nanobiotechnology · 2025Article
- Gender matters: factors important for quality of life in midlife after stroke.Frontiers in neurology · 2025Article
- Frontal Pole Neuromodulation for Impulsivity and Suicidality in Veterans With Mild Traumatic Brain Injury and Common Co-Occurring Mental Health Conditions: Protocol for a Pilot Randomized Controlled Trial.JMIR research protocols · 2024Article
- Performance of the Rivermead Post-Concussion Questionnaire in a sample of people with traumatic brain injury living in Italy.European journal of physical and rehabilitation medicine · 2024Article
- Biopsychosocial factors of quality of life in individuals with moderate to severe traumatic brain injury: a scoping review.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024Article
- Reference Values for the German Version of the Quality of Life after Brain Injury in Children and Adolescents (QOLIBRI-KID/ADO) from a General Population Sample.Journal of personalized medicine · 2024Article
- Quality of Life Following Traumatic Brain Injury in Iraqi Patients.Ethiopian journal of health sciences · 2024Article
- The Effects of Early Life History of TBI on the Progression of Normal Brain Aging with Implications for Increased Dementia Risk.Advances in neurobiology · 2024Review
- Health-related quality of life among inpatients suffering from Traumatic brain injury in an urban setting in Vietnam.PloS one · 2024Article
- Treatment with Rapamycin in Animal Models of Traumatic Brain Injuries; a Systematic Review and Meta-Analysis.Archives of academic emergency medicine · 2024Review
- Social participation and health-related quality of life before and during the second wave of the Covid-19 pandemic in individuals with traumatic brain injury: A follow-up exploratory correlational study.Journal of rehabilitation medicine · 2023Article
Corrections and comments
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Authors and funding
7 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTraumatic brain injury (TBI) is the leading cause of death and disability among children and young adults in industrialized countries, but strikingly little is known how patients cope with the long-term consequences of TBI. Thus, the aim of the current study was to elucidate health-related quality of life (HRQoL) and outcome predictors in chronic TBI adults.
methodsIn this cross-sectional study, 439 former patients were invited to report HRQoL up to 10 years after mild, moderate or severe TBI using the QOLIBRI (Quality of Life after Brain Injury) questionnaire. The QOLIBRI total score has a maximum score of 100. A score below 60 indicates an unfavorable outcome with an increased risk of an affective and/or anxiety disorder. Results were correlated with demographics and basic characteristics received from medical records (TBI severity, etiology, age at TBI, age at survey, time elapsed since TBI, and sex) using regression models. Differences were considered significant at p < 0.05.
resultsFrom the 439 invited patients, 135 out of 150 in principle eligible patients (90%) completed the questionnaire; 76% were male, and most patients experienced severe TBI due to a traffic-related accident (49%) or a fall (44%). The mean QOLIBRI total score was 65.5 (± 22.6), indicating good HRQoL. Factors for higher level of satisfaction (p = 0.03; adjusted R
conclusionsThe majority of chronic TBI patients reported good HRQoL and the initial TBI severity is a slight contributor but not a strong predictor of HRQoL. Autonomy and cognition are decisive factors for satisfied outcome and should be clearly addressed in neurorehabilitation. One third of patients, however, suffer from unsatisfactory outcome with psychiatric sequelae. Thus, an early neuropsychiatric assessment after TBI is necessary and need to be installed in future TBI guidelines.
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