ReviewAntioxidants (Basel, Switzerland)2020
Determination of Polyphenols Using Liquid Chromatography-Tandem Mass Spectrometry Technique (LC-MS/MS): A Review.
Review in Antioxidants (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers.
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Who cites it
74 citing papers in PubMed.
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- New Insights into the Antimicrobial and Wound-Healing Properties of Turmeric-Powder-DerivedBiomedicines · 2026Article
- Blueberry Extract as a Source of Natural Antioxidants to Improve Thermal Stability of Standard Sunflower Oil.Antioxidants (Basel, Switzerland) · 2026Article
- Comparative Evaluation of Pesticidal Potential of Five Aromatic Plants, with Emphasis on the Fungicidal Activity ofMicroorganisms · 2026Article
- Polyphenol Composition, Antioxidant Properties, and Health Benefits of Moroccan-Cultivated Raspberries, Blackberries, and Blueberries: A Comprehensive Review.Foods (Basel, Switzerland) · 2026Review
- Andean Tuber Ulluco (Foods (Basel, Switzerland) · 2026Article
- Plant-derived phenolic acids in Shilajit: a comparative HPLC-MS/MS analysis across five regions.Scientific reports · 2026Article
- Valorization of Onion By-Products and Assessment of Their Biological Activities.Foods (Basel, Switzerland) · 2026Article
- Polyphenols in Sugar Beet Leaves: Composition, Variability, and Valorization Opportunities.Molecules (Basel, Switzerland) · 2026Article
- Ultrasound-assisted deep eutectic solvent extraction of polyphenols from peach leaves and their compositional characterization.Frontiers in nutrition · 2026Article
- A New Algal Friendly Extract fromMarine drugs · 2025Article
14 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In recent years, the consumption of polyphenols has been increasing, largely due to its beneficial effects on health. They are present in a wide variety of foods, but their extraction and characterization are complicated since they are mostly in complex matrices. For this reason, the use of selective, sensitive, and versatile analytical techniques such as liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) is necessary. In this review, the most relevant studies of the last years regarding the analysis of polyphenols in different matrices by comprehensive LC-MS/MS are discussed. Relevant steps such as extraction, sample purification, and chromatographic analysis methods are emphasized. In particular, the following methodological aspects are discussed: (a) the proper selection of the extraction technique, (b) the extraction and elution solvents, (c) the purification step, (d) the selection of both stationary and mobile phases for the chromatographic separation of compounds, and (e) the different conditions for mass spectrometry. Overall, this review presents the data from the most recent studies, in a comprehensive way, thus providing and simplifying the information of the great variety of works that exist in the literature on this wide topic.
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