Evidence map›Paper›PMID 32498399›Full record

ArticleViruses2020

Reduced-Beclin1-Expressing Mice Infected with Zika-R103451 and Viral-Associated Pathology during Pregnancy.

Mohan Kumar Muthu Karuppan, Chet Raj Ojha, Myosotys Rodriguez, Jessica Lapierre, M Javad Aman, Fatah Kashanchi, Michal Toborek, Madhavan Nair, Nazira El-Hage

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Viruses, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Mohan Kumar Muthu KaruppanDepartment of Immunology and Nanomedicine, Herbert Wertheim College of Medicine, Florida International University, Miami, FL 33199, USA.ORCID 0000-0002-2795-5689
Chet Raj OjhaDepartment of Immunology and Nanomedicine, Herbert Wertheim College of Medicine, Florida International University, Miami, FL 33199, USA.ORCID 0000-0002-6816-8892
Myosotys RodriguezDepartment of Immunology and Nanomedicine, Herbert Wertheim College of Medicine, Florida International University, Miami, FL 33199, USA.
Jessica LapierreDepartment of Immunology and Nanomedicine, Herbert Wertheim College of Medicine, Florida International University, Miami, FL 33199, USA.ORCID 0000-0002-0606-9792
M Javad AmanIntegrated Biotherapeutics, Rockville, MD 20850, USA.ORCID 0000-0001-6977-4707
Fatah KashanchiNational Center for Biodefense and Infectious Diseases, George Mason University, Manassas, VA 20110, USA.
Michal ToborekDepartment of Biochemistry and Molecular Biology, University of Miami Miller School of Medicine, Miami, FL 33136, USA.ORCID 0000-0003-4475-2119
Madhavan NairDepartment of Immunology and Nanomedicine, Herbert Wertheim College of Medicine, Florida International University, Miami, FL 33199, USA.
Nazira El-HageDepartment of Immunology and Nanomedicine, Herbert Wertheim College of Medicine, Florida International University, Miami, FL 33199, USA.
Florida International University · USGeorge Mason University · USIntegrated BioTherapeutics (United States) · USUniversity of Miami · US

Funding

NIH HHS DA036154
6 · The paper itself

Abstract

Here, we used a mouse model with defective autophagy to further decipher the role of Beclin1 in the infection and disease of Zika virus (ZIKV)-R103451. Hemizygous (

Indexed as

AnimalsAutophagyBeclin-1BrainDisease Models, AnimalFemaleGene Knockdown TechniquesHemizygoteHumansInsulin-Like Growth Factor IMaleMiceMice, Inbred C57BLPregnancyPregnancy Complications, InfectiousZika VirusBeclin-1Becn1 protein, mouseInsulin-Like Growth Factor Iautophagy-defective mouse-modelBeclin1congenital syndromegrowth factorinflammatory moleculesmicrocephalyZika virus

Identifiers

PMID32498399
PMCPMC7354588
OpenAlexW3033433483

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.