Evidence map›Paper›PMID 32498389›Full record

ArticleJournal of clinical medicine2020

The Circulating Fatty Acid Transporter Soluble CD36 Is Not Associated with Carotid Atherosclerosis in Subjects with Type 1 and Type 2 Diabetes Mellitus.

Esmeralda Castelblanco, Lucía Sanjurjo, Maria Barranco-Altirriba, Mireia Falguera, Marta Hernández, Berta Soldevila, Maria-Rosa Sarrias, Josep Franch-Nadal, Juan Antonio Arroyo, José-Manuel Fernandez-Real and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 1 country.

Esmeralda CastelblancoDepartment of Endocrinology & Nutrition, Hospital de la Santa Creu i Sant Pau, IIB Sant Pau, 08041 Barcelona, Spain.ORCID 0000-0002-2061-6270
Lucía SanjurjoInnate Immunity Group, Health Sciences Research Institute Germans Trias i Pujol (IGTP), 08916 Badalona, Spain.
Maria Barranco-AltirribaDepartment of Endocrinology & Nutrition, Hospital de la Santa Creu i Sant Pau, IIB Sant Pau, 08041 Barcelona, Spain.
Mireia FalgueraBiomedical Research Institute of Lleida, University of Lleida, 25198 Lleida, Spain.
Marta HernándezBiomedical Research Institute of Lleida, University of Lleida, 25198 Lleida, Spain.ORCID 0000-0003-1237-298X
Berta SoldevilaCentre for Biomedical Research on Diabetes and Associated Metabolic Diseases (CIBERDEM), 08907 Barcelona, Spain.
Maria-Rosa SarriasInnate Immunity Group, Health Sciences Research Institute Germans Trias i Pujol (IGTP), 08916 Badalona, Spain.ORCID 0000-0001-6929-8069
Josep Franch-NadalCentre for Biomedical Research on Diabetes and Associated Metabolic Diseases (CIBERDEM), 08907 Barcelona, Spain.
Juan Antonio ArroyoDepartment of Internal Medicine, Hypertension and Vascular Risk Unit, Hospital de la Santa Creu i Sant Pau, 08041 Barcelona, Spain.
José-Manuel Fernandez-RealDepartment of Diabetes, Endocrinology & Nutrition, Hospital Dr Josep Trueta, IDIBGI, 17007 Girona, Spain.
Nuria AlonsoCentre for Biomedical Research on Diabetes and Associated Metabolic Diseases (CIBERDEM), 08907 Barcelona, Spain.
Didac MauricioDepartment of Endocrinology & Nutrition, Hospital de la Santa Creu i Sant Pau, IIB Sant Pau, 08041 Barcelona, Spain.ORCID 0000-0002-2868-0250
Universitat Autònoma de Barcelona · ESCentro de Investigación Biomédica en Red Diabetes y Enfermedades Metabólicas Asociadas · ESHospital de Sant Pau · ESUniversitat de Lleida · ESCentre for Biomedical Network Research on Rare Diseases · ESInstitut d'Investigació Biomèdica de Girona · ESInstitut d'Investigació en Ciències de la Salut Germans Trias i Pujol · ES

Funding

European Association for the Study of Diabetes 2014-EFSD-00914
6 · The paper itself

Abstract

This study aimed to determine the association of fatty acid transporter plasma soluble cluster of differentiation 36 (sCD36) with subclinical carotid atherosclerosis (SCA). A cross-sectional study was conducted in 1023 subjects, 225 with type 1 diabetes (T1D), 276 with type 2 diabetes (T2D) and 522 who were nondiabetic. Carotid atherosclerotic plaque (CAP) presence was determined using B-mode carotid ultrasound imaging. sCD36 were analysed by ELISA, and CD36 surface receptor and mRNA expression were measured by flow cytometry and real-time PCR. Logistic regression models were used to evaluate sCD36 as a biomarker of SCA. Up to 376 (36.75%) participants had at least one CAP, 76 T1D, 164 T2D and 136 without diabetes, while the remaining 647 (63.25%) did not have any CAP. There were no differences in sCD36 between patients with and without CAP in T1D (

Indexed as

atherosclerotic plaquecarotid atherosclerosissCD36type 1 diabetes mellitustype 2 diabetes mellitus

Identifiers

PMID32498389
PMCPMC7355534
OpenAlexW3033533395

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.