Evidence map›Paper›PMID 32498372›Full record

Trial reportNutrients2020

A Double-Blind, Randomized Placebo-Controlled Trial of Probiotic

Jane Macnaughtan, Francesco Figorilli, Elisabet García-López, Haw Lu, Helen Jones, Rohit Sawhney, Kaori Suzuki, Sarah Fairclough, Joanne Marsden, Alba Moratella and 7 more

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 7 pooled it
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 7 syntheses or guidelines pooled it, 49 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 7 institutions in 3 countries.

Jane MacnaughtanUCL Institute for Liver and Digestive Health, Division of Medicine, University College London, London NW3 2PF, UK.
Francesco FigorilliUCL Institute for Liver and Digestive Health, Division of Medicine, University College London, London NW3 2PF, UK.
Elisabet García-LópezData Management Centre, European Foundation for the Study of Chronic Liver Failure (EF-CLIF), 08021 Barcelona, Spain.ORCID 0000-0003-3160-4563
Haw LuUCL Institute for Liver and Digestive Health, Division of Medicine, University College London, London NW3 2PF, UK.
Helen JonesUCL Institute for Liver and Digestive Health, Division of Medicine, University College London, London NW3 2PF, UK.
Rohit SawhneyUCL Institute for Liver and Digestive Health, Division of Medicine, University College London, London NW3 2PF, UK.
Kaori SuzukiYakult Europe B.V., 1332 EN Almere, The Netherlands.
Sarah FaircloughMid and South Essex NHS Foundation Trust, Basildon & Thurrock University Hospitals NHS Foundation Trust, Basildon, SS16 5NL, UK.
Joanne MarsdenDepartment of Biochemistry, Bessemer Wing, King's College Hospital, London SE5 9RS, UK.
Alba MoratellaUCL Institute for Liver and Digestive Health, Division of Medicine, University College London, London NW3 2PF, UK.
I Jane CoxInstitute of Hepatology London, Foundation for Liver Research, London SE5 9NT, UK.
Linda ThomasYakult Europe B.V., 1332 EN Almere, The Netherlands.
Nathan DaviesUCL Institute for Liver and Digestive Health, Division of Medicine, University College London, London NW3 2PF, UK.
Roger WilliamsInstitute of Hepatology London, Foundation for Liver Research, London SE5 9NT, UK.
Raj MookerjeeUCL Institute for Liver and Digestive Health, Division of Medicine, University College London, London NW3 2PF, UK.
Gavin WrightUCL Institute for Liver and Digestive Health, Division of Medicine, University College London, London NW3 2PF, UK.
Rajiv JalanUCL Institute for Liver and Digestive Health, Division of Medicine, University College London, London NW3 2PF, UK.
University College London · GBKing's College London · GBThe Royal Free Hospital · GBYakult (Netherlands) · NLBasildon and Thurrock University Hospitals NHS Foundation Trust · GBEuropean Foundation for the Study of Chronic Liver Failure · ESKing's College Hospital · GB

Funding

Yakult Honsha N/A
6 · The paper itself

Abstract

Background

Indexed as

Dietary SupplementsLacticaseibacillus caseiAdolescentAdultAgedChemokine CCL2Chemokine CCL4Double-Blind MethodFemaleGastrointestinal MicrobiomeHumansInflammationInterleukin-17Interleukin-1betaLiver CirrhosisMaleCCL2 protein, humanChemokine CCL2Chemokine CCL4IL17A protein, humanInterleukin-17Interleukin-1betacirrhosiscytokineneutrophilprobiotic

Identifiers

PMID32498372
PMCPMC7352321
OpenAlexW3033006882

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.