ReviewJournal of clinical medicine2020
Optical Coherence Tomography Angiography in Neurodegenerative Disorders.
Review in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
46 citing papers in PubMed, 3 syntheses or guidelines pooled it, 78 citations in OpenAlex.
- Optical coherence tomography angiography measurements in Parkinson's disease: A systematic review and meta-analysis.Eye (London, England) · 2023Pooled it
- Pooled it
- Quantitative ophthalmic posterior segment optical coherence tomography angiography and neurologic conditions: a review.Frontiers in neurologyPooled it
- Clinical validation of artificial intelligence algorithms for the detection of different central-involved retinal pathologies and glaucoma from non-mydriatic images.Frontiers in artificial intelligence · 2026Trial
- Diagnostic Role of Multimodal Imaging in Optic Disc Diseases.Diagnostics (Basel, Switzerland) · 2026Review
- The Eye and the Brain: Photonic Devices in Neuro-Ophthalmology.Diseases (Basel, Switzerland) · 2026Review
- Optical coherence tomography angiography assessment of macular and peripapillary microvasculature in Parkinson's disease.BMC ophthalmology · 2026Article
- Evaluation of the Electroconvulsive Therapy's Impact on Retinal Structures in First-Episode Psychosis Patients Using Optical Coherence Tomography.Schizophrenia bulletin · 2026Article
- Retinal Microvascular Biomarkers Measured by Optical Coherence Tomography Angiography in Neurodegenerative and Neurovascular Disorders: A Systematic Review and Meta-Analysis.Clinical ophthalmology (Auckland, N.Z.) · 2026Review
- Comparison of OCT Structural Parameters and OCTA-Measured Retinal Vessel Density and Peripapillary Choroidal Microvasculature in Glaucoma and Optic Neuritis From Multiple Sclerosis or Neuromyelitis Optica.Journal of ophthalmology · 2026Article
- Radial Peripapillary Capillary Vessel Density as a New Biomarker in Pseudophakic Cystoid Macular Edema.Journal of clinical medicine · 2025Article
- Assessment of retinal blood flow changes in early Parkinson's disease: An optical coherence tomography angiography study.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2025Article
- Retina as a potential biomarker for the early stage of Alzheimer's disease spectrum.Annals of clinical and translational neurology · 2024Article
- Severity Stratification of Coronary Artery Disease Using Novel Inner Ellipse-Based Foveal Avascular Zone Biomarkers.Investigative ophthalmology & visual science · 2024Article
- Optical coherence tomography angiography as a potential tool in differential diagnosis of multiple sclerosis and rheumatic disorders with central nervous system involvement.International ophthalmology · 2024Article
- Retinal small vessel pathology is associated with disease burden in multiple sclerosis.Multiple sclerosis (Houndmills, Basingstoke, England) · 2024Article
- Arterial spin labeling reveals disordered cerebral perfusion and cerebral blood flow-based functional connectivity in primary open-angle glaucoma.Brain imaging and behavior · 2024Article
- Article
- Evaluation of the Vascular Network with Optical Coherens Tomography Angiography in Multiple Sclerosis and its Relationship with the Clinic.Noro psikiyatri arsivi · 2024Article
- Association of preoperative retinal microcirculation and perioperative outcomes in patients undergoing congenital cardiac surgery.Orphanet journal of rare diseases · 2023Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 9 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Retinal microcirculation shares similar features with cerebral small blood vessels. Thus, the retina may be considered an accessible 'window' to detect the microvascular damage occurring in the setting of neurodegenerative disorders. Optical coherence tomography angiography (OCT-A) is a non-invasive imaging modality providing depth resolved images of blood flow in the retina, choroid, and optic nerve. In this review, we summarize the current literature on the application of OCT-A in glaucoma and central nervous system conditions such as Alzheimer's disease, Parkinson's disease, and multiple sclerosis. Future directions aiming at evaluating whether OCT-A can be an additional biomarker for the early diagnosis and monitoring of neurodegenerative disorders are also discussed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.