Evidence map›Paper›PMID 32498331›Full record

ArticleMarine drugs2020

Enzyme-Assisted Fucoidan Extraction from Brown Macroalgae

Thuan Thi Nguyen, Maria Dalgaard Mikkelsen, Vy Ha Nguyen Tran, Vo Thi Dieu Trang, Nanna Rhein-Knudsen, Jesper Holck, Anton B Rasin, Hang Thi Thuy Cao, Tran Thi Thanh Van, Anne S Meyer

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
16.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 136 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Thuan Thi NguyenProtein Chemistry and Enzyme Technology Section, DTU Bioengineering, Department of Biotechnology and Biomedicine, Technical University of Denmark, Building 221, 2800 Kongens Lyngby, Denmark.
Maria Dalgaard MikkelsenProtein Chemistry and Enzyme Technology Section, DTU Bioengineering, Department of Biotechnology and Biomedicine, Technical University of Denmark, Building 221, 2800 Kongens Lyngby, Denmark.
Vy Ha Nguyen TranProtein Chemistry and Enzyme Technology Section, DTU Bioengineering, Department of Biotechnology and Biomedicine, Technical University of Denmark, Building 221, 2800 Kongens Lyngby, Denmark.
Vo Thi Dieu TrangProtein Chemistry and Enzyme Technology Section, DTU Bioengineering, Department of Biotechnology and Biomedicine, Technical University of Denmark, Building 221, 2800 Kongens Lyngby, Denmark.
Nanna Rhein-KnudsenProtein Chemistry and Enzyme Technology Section, DTU Bioengineering, Department of Biotechnology and Biomedicine, Technical University of Denmark, Building 221, 2800 Kongens Lyngby, Denmark.ORCID 0000-0001-6695-346X
Jesper HolckProtein Chemistry and Enzyme Technology Section, DTU Bioengineering, Department of Biotechnology and Biomedicine, Technical University of Denmark, Building 221, 2800 Kongens Lyngby, Denmark.ORCID 0000-0002-8072-1101
Anton B RasinG.B. Elyakov Pacific Institute of Bioorganic Chemistry, Far-Eastern Branch of the Russian Academy of Sciences, 159, Prospect 100-let Vladivostoku, Vladivostok 690022, Russia.
Hang Thi Thuy CaoNhaTrang Institute of Technology Research and Application, Vietnam Academy of Science and Technology, 02 Hung Vuong Street, Nhatrang 650000, Vietnam.
Tran Thi Thanh VanNhaTrang Institute of Technology Research and Application, Vietnam Academy of Science and Technology, 02 Hung Vuong Street, Nhatrang 650000, Vietnam.
Anne S MeyerProtein Chemistry and Enzyme Technology Section, DTU Bioengineering, Department of Biotechnology and Biomedicine, Technical University of Denmark, Building 221, 2800 Kongens Lyngby, Denmark.ORCID 0000-0001-8910-9931
Vietnam Academy of Science and Technology · VNTechnical University of Denmark · DKPacific Institute of Bioorganic Chemistry. GB Elyakova Far Eastern Branch of the Russian Academy of Sciences · RU

Funding

EU Interreg-Deutchland-Denmark Grant FucosanInnovationsfonden Grant no. 5157-000003BMinistry of Science and Technology of Vietnam ĐTĐL.CN-57/19
6 · The paper itself

Abstract

Fucoidans from brown macroalgae (brown seaweeds) have different structures and many interesting bioactivities. Fucoidans are classically extracted from brown seaweeds by hot acidic extraction. Here, we report a new targeted enzyme-assisted methodology for fucoidan extraction from brown seaweeds. This enzyme-assisted extraction protocol involves a one-step combined use of a commercial cellulase preparation (Cellic

Indexed as

CellulasePolysaccharide-LyasesFucusPhaeophyceaePolysaccharidesSeaweedCellulasefucoidanpoly(beta-D-mannuronate) lyasePolysaccharide-LyasesPolysaccharidesalginate lyasecellulasechemical extractionenzymatic extractionfucose-containing sulfated polysaccharidesFucus evanescens

Identifiers

PMID32498331
PMCPMC7344474
OpenAlexW3033625435

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.