Evidence map›Paper›PMID 32498275›Full record

ArticleInternational journal of molecular sciences2020

Skeletal Muscle Gene Expression in Long-Term Endurance and Resistance Trained Elderly.

Alessandra Bolotta, Giuseppe Filardo, Provvidenza Maria Abruzzo, Annalisa Astolfi, Paola De Sanctis, Alessandro Di Martino, Christian Hofer, Valentina Indio, Helmut Kern, Stefan Löfler and 4 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 27 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Review
  6. Effects of aging on calcium channels in skeletal muscle.Frontiers in molecular biosciences · 2025
    Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Non-coding RNA basis of muscle atrophy.Molecular therapy. Nucleic acids · 2021
    Review
  13. Editorial for the Special Issue "Molecular Bases of Senescence".International journal of molecular sciences · 2021
    Article
  14. Review
  15. Article
  16. Frontiers in physiology · 2021
    Article
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 8 institutions in 2 countries.

Alessandra BolottaDepartment of Experimental, Diagnostic and Specialty Medicine, University of Bologna School of Medicine, 40138 Bologna, Italy.
Giuseppe FilardoApplied and Translational Research Center, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.
Provvidenza Maria AbruzzoDepartment of Experimental, Diagnostic and Specialty Medicine, University of Bologna School of Medicine, 40138 Bologna, Italy.
Annalisa AstolfiGiorgio Prodi Interdepartimental Center for Cancer Research, S.Orsola-Malpighi Hospital, 40138 Bologna, Italy.ORCID 0000-0002-2732-0747
Paola De SanctisDepartment of Experimental, Diagnostic and Specialty Medicine, University of Bologna School of Medicine, 40138 Bologna, Italy.
Alessandro Di MartinoSecond Orthopaedic and Traumatologic Clinic, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.
Christian HoferLudwig Boltzmann Institute for Rehabilitation Research, 1160 Wien, Austria.
Valentina IndioGiorgio Prodi Interdepartimental Center for Cancer Research, S.Orsola-Malpighi Hospital, 40138 Bologna, Italy.ORCID 0000-0002-8854-3821
Helmut KernLudwig Boltzmann Institute for Rehabilitation Research, 1160 Wien, Austria.
Stefan LöflerLudwig Boltzmann Institute for Rehabilitation Research, 1160 Wien, Austria.ORCID 0000-0002-6592-0663
Maurilio MarcacciDepartment of Biomedical Sciences, Knee Joint Reconstruction Center, 3rd Orthopaedic Division, Humanitas Clinical Institute, Humanitas University, 20089 Milan, Italy.
Sandra ZampieriDepartment of Surgery, Oncology and Gastroenterology, University of Padua, 35122 Padua, Italy.
Marina MariniDepartment of Experimental, Diagnostic and Specialty Medicine, University of Bologna School of Medicine, 40138 Bologna, Italy.ORCID 0000-0003-1932-7380
Cinzia ZucchiniDepartment of Experimental, Diagnostic and Specialty Medicine, University of Bologna School of Medicine, 40138 Bologna, Italy.
Don Carlo Gnocchi Foundation · ITLudwig Boltzmann Institute for Cancer Research · ATIstituto Ortopedico Rizzoli · ITUniversity of Bologna · ITHumanitas University · ITIRCCS Azienda Ospedliero-Universitaria di Bologna Policlinico di Sant'Orsola · ITUniversity of Ferrara · ITUniversity of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Physical exercise is deemed the most efficient way of counteracting the age-related decline of skeletal muscle. Here we report a transcriptional study by next-generation sequencing of vastus lateralis biopsies from elderly with a life-long high-level training practice (

Indexed as

Physical EnduranceResistance TrainingAgedAMP-Activated Protein KinasesAnthropometryAthletesBiopsyCalciumCellular SenescenceGene Expression RegulationHumansInflammationMaleMitochondriaMuscle, SkeletalRibosomesAMP-Activated Protein KinasesCalciumMTOR protein, humanThyroid HormonesTOR Serine-Threonine Kinasesagingendurance and resistance trainingexercisegene expressionsarcopeniaskeletal muscle

Identifiers

PMID32498275
PMCPMC7312229
OpenAlexW3033155331

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.