ReviewJournal of clinical medicine2020
What Is the Impact of Intraoperative Microscope-Integrated OCT in Ophthalmic Surgery? Relevant Applications and Outcomes. A Systematic Review.
Review in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.
- Synthesis of the clinical utilities and issues of intraoperative imaging devices in clinical reports: a systematic review and thematic synthesis.BMC medical informatics and decision making · 2025Pooled it
- Fast robot-to-iOCT calibration using conical geometry and 2D cross-scan OCT.Journal of biomedical optics · 2026Article
- Retinal glial cell removing during internal limiting membrane peeling is associated with higher-stage idiopathic epiretinal membrane.Eye and vision (London, England) · 2026Article
- [Real-time OCT-guided strategies for optimization of precision and safety in vitreoretinal surgery].Die Ophthalmologie · 2026Review
- Pixel-Level Segmented Longitudinal Optical Coherence Tomography Data of Macular Hole Surgery Outcomes.Scientific data · 2026Article
- Application of digital surgery in ophthalmology: intraoperative display of pre-operative enface OCT and ERM peeling unveiling the role of ERM adherence.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
- Toward comprehensive real-time scene understanding in ophthalmic surgery through multimodal image fusion.International journal of computer assisted radiology and surgery · 2026Article
- Performance of a prototype electric silicone oil injector and aspirator in vitreoretinal surgery.Frontiers in medicine · 2026Article
- The Feasibility and Clinical Evaluation of an Immersive Augmented Reality Surgical Headset Integrated with Swept-Source Intraoperative Optical Coherence Tomography for Ophthalmic Surgery in the DISCOVER Study.Diagnostics (Basel, Switzerland) · 2025Article
- Techniques for subretinal injections in animals.Veterinary ophthalmology · 2025Review
- New Directions for Ophthalmic OCT - Handhelds, Surgery, and Robotics.Translational vision science & technology · 2025Review
- Stapler for corneal transplantation: a hypothesis.Medical hypothesis, discovery & innovation ophthalmology journal · 2025Article
- Optical coherence tomography (OCT) and OCT angiography: Technological development and applications in brain science.Theranostics · 2025Review
- Oxidative Stress Mediates Epigenetic Modifications and the Expression of miRNAs and Genes Related to Apoptosis in Diabetic Retinopathy Patients.Journal of clinical medicine · 2023Article
- Methods for real-time feature-guided image fusion of intrasurgical volumetric optical coherence tomography with digital microscopy.Biomedical optics express · 2023Article
- Pediatric Glaucoma-From Screening, Early Detection to Management.Children (Basel, Switzerland) · 2023Review
- Intraoperative Optical Coherence Tomography in the Management of Macular Holes: State of the Art and Future Perspectives.Biomedicines · 2022Review
- Intraoperative Anterior Segment Optical Coherence Tomography in the Management of Cataract Surgery: State of the Art.Journal of clinical medicine · 2022Review
- Portable boom-type ultrahigh-resolution OCT with an integrated imaging probe for supine position retinal imaging.Biomedical optics express · 2022Article
- Outcomes of the advanced visualization in corneal surgery evaluation trial; a non-inferiority randomized control trial to evaluate the use of intraoperative OCT during Descemet membrane endothelial keratoplasty.Frontiers in ophthalmology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOptical coherence tomography (OCT) has recently been introduced in the operating theatre. The aim of this review is to present the actual role of microscope-integrated optical coherence tomography (MI-OCT) in ophthalmology.
methodA total of 314 studies were identified, following a literature search adhering to the preferred reporting items for systematic reviews and meta-analyses (PRISMA) guidelines. After full-text evaluation, 81 studies discussing MI-OCT applications in ophthalmology were included.
resultsAt present, three microscope-integrated optical coherence tomography systems are commercially available. MI-OCT can help anterior and posterior segment surgeons in the decision-making process, providing direct visualization of anatomic planes before and after surgical manoeuvres, assisting in complex cases, and detecting or confirming intraoperative complications. Applications range from corneal transplant to macular surgery, including cataract surgery, glaucoma surgery, paediatric examination, proliferative diabetic retinopathy surgery, and retinal detachment surgery.
conclusionThe use of MI-OCT in ophthalmic surgery is becoming increasingly prevalent and has been applied in almost all procedures. However, there are still limitations to be overcome and the technology involved remains difficult to access and use.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.