Evidence map›Paper›PMID 32497783›Full record

ArticleContemporary clinical trials2020

Study protocol: Using peer support to aid in prevention and treatment in prediabetes (UPSTART).

Michele Heisler, Jeffrey Kullgren, Caroline Richardson, Shelley Stoll, Cristina Alvarado Nieves, Deanne Wiley, Tali Sedgwick, Alyce Adams, Monique Hedderson, Eileen Kim and 2 more

Registry-linked trialAbstract readClinical Trial Protocol
In one paragraph

Article in Contemporary clinical trials, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03689530 (UPSTART), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03689530 nacompletednot on this map

UPSTART: Using Peer Support to Aid in Prevention and Treatment in Prediabetes

TypeinterventionalSponsorUniversity of MichiganRan2018 to 2022Enrolled450ConditionsPreDiabetesArmsPeer Support, Enhanced Usual Care
3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Using Peer Support to Prevent Diabetes: Results of a Pragmatic RCT.American journal of preventive medicine · 2023
    Trial
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Michele HeislerDepartment of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, United States of America; VA Center for Clinical Management Research, VA Ann Arbor Healthcare System, Ann Arbor, MI, United States of America. Electronic address: mheisler@umich.edu.
Jeffrey KullgrenDepartment of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, United States of America; VA Center for Clinical Management Research, VA Ann Arbor Healthcare System, Ann Arbor, MI, United States of America; Department of Health Management and Policy, University of Michigan School of Public Health, Ann Arbor, MI, United States of America; University of Michigan Institute for Healthcare Policy and Innovation, Ann Arbor, MI, United States of America. Electronic address: jkullgre@med.umich.edu.
Caroline RichardsonDepartment of Family Medicine, University of Michigan Medical School, Ann Arbor, MI, United States of America. Electronic address: caroli@umich.edu.
Shelley StollDepartment of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, United States of America. Electronic address: scstoll@umich.edu.
Cristina Alvarado NievesUniversity of Michigan, Department of Internal Medicine- Metabolism, Endocrinology and Diabetes, United States of America. Electronic address: alvaradc@med.umich.edu.
Deanne WileyKaiser Permanente Northern California, United States of America. Electronic address: deanne.wiley@kp.org.
Tali SedgwickKaiser Permanente Northern California Division of Research, United States of America. Electronic address: Tali.S.Sedgwick@kp.org.
Alyce AdamsKaiser Permanente Northern California, United States of America. Electronic address: Alyce.S.Adams@kp.org.
Monique HeddersonKaiser Permanente Northern California, United States of America. Electronic address: Monique.m.hedderson@kp.org.
Eileen KimThe Permanente Medical Group (Kaiser Permanente, Northern California), United States of America. Electronic address: Eileen.Kim@kp.org.
Megan RaoThe Permanente Medical Group (Kaiser Permanente, Northern California), United States of America. Electronic address: megan.rao@kp.org.
Julie A SchmittdielKaiser Permanente Northern California Division of Research, United States of America. Electronic address: Julie.A.Schmittdiel@kp.org.

Funding

Research BaseP30DK092926 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MARY ELLEN MICHELE HEISLER, ADESUWA B OLOMU · 2011 to 2026
$10.0M
Translational Research Core - Health Engagement & Action Translational (HEAT)P30DK092924 · NIDDK · KAISER FOUNDATION RESEARCH INSTITUTE · PI Alyce Sophia Adams, HILARY Kessler SELIGMAN · 2011 to 2026
$9.2M
Using Peer Support To Aid in PRevention and Treatment in Prediabetes (UPSTART)R18DK113403 · NIDDK · KAISER FOUNDATION RESEARCH INSTITUTE · PI HEISLER, MARY ELLEN MICHELE, SCHMITTDIEL, JULIE A · 2017 to 2021
$3.3M
NIDDK NIH HHS P30 DK092924NIDDK NIH HHS P30 DK092926NIDDK NIH HHS R18 DK113403
6 · The paper itself

Abstract

backgroundThere is an urgent need to develop and evaluate effective and scalable interventions to prevent or delay the onset of type 2 diabetes mellitus (T2DM).

methodsIn this randomized controlled pragmatic trial, 296 adults with prediabetes will be randomized to either a peer support arm or enhanced usual care. Participants in the peer support arm meet face-to-face initially with a trained peer coach who also is a patient at the same health center to receive information on locally available wellness and diabetes prevention programs, discuss behavioral goals related to diabetes prevention, and develop an action plan for the next week to meet their goals. Over six months, peer coaches call their assigned participants weekly to provide support for weekly action steps. In the final 6 months, coaches call participants at least once monthly. Participants in the enhanced usual care arm receive information on local resources and periodic updates on available diabetes prevention programs and resources. Changes in A1c, weight, waist circumference and other patient-centered outcomes and mediators and moderators of intervention effects will be assessed.

resultsAt least 296 participants and approximately 75 peer supporters will be enrolled. DISCUSSION: Despite evidence that healthy lifestyle interventions can improve health behaviors and reduce risk for T2DM, engagement in recommended behavior change is low. This is especially true among racial and ethnic minority and low-income adults. Regular outreach and ongoing support from a peer coach may help participants to initiate and sustain healthy behavior changes to reduce their risk of diabetes.

trial registrationThe ClinicalTrials.gov registration number is NCT03689530.

Indexed as

Diabetes Mellitus, Type 2Prediabetic StateAdultCounselingEthnicityHumansMinority GroupsPragmatic Clinical Trials as TopicRandomized Controlled Trials as TopicDiabetes preventionHealth coachingPeer-supportRandomized controlled trials

Identifiers

PMID32497783
PMCPMC8059966

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.