Evidence map›Paper›PMID 32497558›Full record

ReviewAlcohol (Fayetteville, N.Y.)2020

Role of non-Genetic Risk Factors in Exacerbating Alcohol-related organ damage.

Natalia A Osna, Rakesh Bhatia, Christopher Thompson, Surinder K Batra, Sushil Kumar, Yeonhee Cho, Gyongyi Szabo, Patricia E Molina, Steven A Weinman, Murali Ganesan and 1 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Alcohol (Fayetteville, N.Y.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Natalia A OsnaResearch Service, Veterans Affairs Nebraska-Western Iowa Health Care System, Omaha, NE, United States; Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE, United States.
Rakesh BhatiaDepartment of Biochemistry & Molecular Biology, University of Nebraska Medical Center, Omaha, NE, United States.
Christopher ThompsonDepartment of Biochemistry & Molecular Biology, University of Nebraska Medical Center, Omaha, NE, United States.
Surinder K BatraDepartment of Biochemistry & Molecular Biology, University of Nebraska Medical Center, Omaha, NE, United States.
Sushil KumarDepartment of Biochemistry & Molecular Biology, University of Nebraska Medical Center, Omaha, NE, United States.
Yeonhee ChoDepartment of Medicine, University of Massachusetts Medical School, Worcester, MA, United States; Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States.
Gyongyi SzaboBeth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, United States.
Patricia E MolinaDepartment of Physiology, LSUHSC-New Orleans, New Orleans, LA, United States.
Steven A WeinmanDepartment of Internal Medicine and the Liver Center, University of Kansas Medical Center, Kansas City, KS, United States.
Murali GanesanResearch Service, Veterans Affairs Nebraska-Western Iowa Health Care System, Omaha, NE, United States; Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE, United States.
Kusum K KharbandaResearch Service, Veterans Affairs Nebraska-Western Iowa Health Care System, Omaha, NE, United States; Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE, United States; Department of Biochemistry & Molecular Biology, University of Nebraska Medical Center, Omaha, NE, United States. Electronic address: kkharbanda@unmc.edu.

Funding

Translational Research/Education ComponentP60AA009803 · NIAAA · LSU HEALTH SCIENCES CENTER · PI DAVID A WELSH · 2004 to 2026
$42.6M
STRUCTURE-FUNCTION RELATIONSHIPS IN THE ALIMENTARY TRACTP30DK034854 · NIDDK · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI WAYNE I LENCER · 1986 to 2026
$32.4M
Role of alcohol adapted Kupffer cells in the progression and resolution of ALDR01AA012863 · NIAAA · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI STEVEN A WEINMAN · 2000 to 2026
$10.2M
Alcohol and Monocyte Signaling Administrative SupplementR01AA011576 · NIAAA · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI Gyongyi Szabo · 1998 to 2026
$9.3M
Project 3: MUC16-Mediated Metabolic Reprograming Induces PC MetastasisP01CA217798 · NCI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI THAYER, SARAH P · 2018 to 2022
$8.1M
TLR4 Signaling in alcoholic liver diseaseR01AA017729 · NIAAA · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI SZABO, GYONGYI · 2009 to 2021
$4.3M
Extracellular vesicles as the vehicles for promoting liver injury induced by HIV and alcoholR01AA027189 · NIAAA · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI OSNA, NATALIA ALEKSANDR, POLUEKTOVA, LARISA Y · 2019 to 2023
$2.6M
Targeting CXCR2 axis in Pancreatic CancerR01CA228524 · NCI · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI BATRA, SURINDER K., SINGH, RAKESH K · 2018 to 2022
$2.0M
Impaired phospholipid methylation results in decreased lipid droplet lipolysis: Role in hepatic steatosisR01AA026723 · NIAAA · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI KHARBANDA, KUSUM K. · 2018 to 2022
$1.6M
Biomarkers of Disease in Alcoholic Hepatitis Administrative SupplementU01AA026933 · NIAAA · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI SZABO, GYONGYI · 2018 to 2023
$1.4M
Ethanol suppresses HBV peptide-MHC Class I presentation on hepatocytesK01AA026864 · NIAAA · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI GANESAN, MURALI · 2018 to 2022
$684k
Precision Medicine Approaches for Alcohol and HIV-associated Dysbiosis, Immune Activation and Cardiometabolic SyndromeUH2AA026226 · NIAAA · LSU HEALTH SCIENCES CENTER · PI MOLINA, PATRICIA E., WELSH, DAVID A · 2017 to 2018
$402k
BLRD VA I01 BX004053NCI NIH HHS P01 CA217798NCI NIH HHS R01 CA228524NIAAA NIH HHS K01 AA026864NIAAA NIH HHS P60 AA009803NIAAA NIH HHS R01 AA011576NIAAA NIH HHS R01 AA012863NIAAA NIH HHS R01 AA017729NIAAA NIH HHS R01 AA026723NIAAA NIH HHS R01 AA027189NIAAA NIH HHS R21 AA026428NIAAA NIH HHS U01 AA026933NIAAA NIH HHS UH2 AA026198NIAAA NIH HHS UH2 AA026226NIDDK NIH HHS P30 DK034854
6 · The paper itself

Abstract

This review provides a summary of the symposium titled "Role of Non-Genetic Risk Factors in Exacerbating Alcohol-Related Organ Damage", which was held at the 42nd Annual Meeting of the Research Society on Alcoholism. The goals of the symposium were to provide newer insights into the role of non-genetic factors, including specific external factors, notably infectious agents or lifestyle factors, that synergistically act to exacerbate alcohol pathogenicity to generate more dramatic downstream biological defects. This summary of the symposium will benefit junior/senior basic scientists and clinicians currently investigating/treating alcohol-induced organ pathology, as well as undergraduate, graduate, and post-graduate students and fellows.

Indexed as

AlcoholismEthanolLife StyleCongresses as TopicHumansRisk FactorsEthanolalcoholHBVHIVinfectious agentsneutrophil extracellular trapssmoking

Identifiers

PMID32497558
PMCPMC7483997

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.