Breast Milk Modulates Transgenerational Immune Inheritance.

Jakob Zimmermann, Andrew J Macpherson

Open access · bronzeAbstract readComment

In one paragraph

Article in Cell, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it

0cells of the map it votes in

7citing papers in PubMed

1.8field-weighted citation impact, top 15% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

The right educational environment: Oral tolerance in early life.Immunological reviews · 2024
Review
A cell transcriptomic profile provides insights into adipocytes of porcine mammary gland across development.Journal of animal science and biotechnology · 2023
Article
Role of human milk oligosaccharide metabolizing bacteria in the development of atopic dermatitis/eczema.Frontiers in pediatrics · 2023
Review
The impact on colostrum oxidative stress, cytokines, and immune cells composition after SARS-CoV-2 infection during pregnancy.Frontiers in immunology · 2022
Article
Breastfeeding Contributes to Physiological Immune Programming in the Newborn.Frontiers in pediatrics · 2021
Review
Role of IgA in the early-life establishment of the gut microbiota and immunity: Implications for constructing a healthy start.Gut microbes
Review
Maternal microbe-specific modulation of the offspring microbiome and development during pregnancy and lactation.Gut microbes
Review

4 · The record

Corrections and comments

Comment on
An Immunologic Mode of Multigenerational Transmission Governs a Gut Treg Setpoint.2020

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jakob ZimmermannMaurice Müller Laboratories (Department for BioMedical Research), Universitätsklinik für Viszerale Chirurgie und Medizin Inselspital, Murtenstrasse 35, University of Bern, 3008 Bern, Switzerland.

Andrew J MacphersonMaurice Müller Laboratories (Department for BioMedical Research), Universitätsklinik für Viszerale Chirurgie und Medizin Inselspital, Murtenstrasse 35, University of Bern, 3008 Bern, Switzerland. Electronic address: andrew.macpherson@dbmr.unibe.ch.

University of Bern · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ROR-γt

Indexed as

Gastrointestinal MicrobiomeT-Lymphocytes, RegulatoryFemaleHumansMilk, HumanNuclear Receptor Subfamily 1, Group F, Member 3Th17 CellsNuclear Receptor Subfamily 1, Group F, Member 3

Identifiers

PMID32497500

DOI10.1016/j.cell.2020.05.030

OpenAlexW3033230153

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.