Evidence map›Paper›PMID 32497101›Full record

ArticlePloS one2020

Defining the volume of consultations for musculoskeletal infection encountered by pediatric orthopaedic services in the United States.

Ryan J Koehler, Benjamin J Shore, Daniel Hedequest, Benton E Heyworth, Colin May, Patricia E Miller, Emily S Rademacher, Ryan M Sanborn, Joshua S Murphy, Alyssa Roseman and 51 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Precision neuroscience.Nature biotechnology · 2025
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

61 authors at 1 institution in 1 country.

Ryan J KoehlerVanderbilt University Medical Center, Monroe Carell Jr. Children's Hospital, Nashville, TN, United States of America,
Benjamin J ShoreBoston Children’s Hospital, Boston, MA, United States of America,
Daniel HedequestBoston Children’s Hospital, Boston, MA, United States of America,
Benton E HeyworthBoston Children’s Hospital, Boston, MA, United States of America,
Colin MayBoston Children’s Hospital, Boston, MA, United States of America,
Patricia E MillerBoston Children’s Hospital, Boston, MA, United States of America,
Emily S RademacherBoston Children’s Hospital, Boston, MA, United States of America,
Ryan M SanbornBoston Children’s Hospital, Boston, MA, United States of America,
Joshua S MurphyChildren’s Healthcare of Atlanta, Atlanta, GA, United States of America,
Alyssa RosemanChildren’s Hospital Colorado, Aurora, CO, United States of America,
Jason W StonebackChildren’s Hospital Colorado, Aurora, CO, United States of America,
Anastasiya A TriznoChildren’s Hospital Colorado, Aurora, CO, United States of America,
Rachel Y GoldsteinChildren’s Hospital of Los Angeles, Los Angeles, CA, United States of America,
Liam HarrisChildren’s Hospital of Los Angeles, Los Angeles, CA, United States of America,
Ena NielsenChildren’s Hospital of Los Angeles, Los Angeles, CA, United States of America,
Divya TalwarChildren’s Hospital of Philadelphia, Philadelphia, PA, United States of America,
Jaime R DenningCincinnati Children’s Hospital Medical Center, Cincinnati, OH, United States of America,
Noor SaaedCincinnati Children’s Hospital Medical Center, Cincinnati, OH, United States of America,
Brooke KutzGillette Children’s Specialty Healthcare, St. Paul, MN, United States of America,
Jennifer C LaineGillette Children’s Specialty Healthcare, St. Paul, MN, United States of America,
Mary NaasGillette Children’s Specialty Healthcare, St. Paul, MN, United States of America,
Walter H TruongGillette Children’s Specialty Healthcare, St. Paul, MN, United States of America,
Matthew RotandoLe Bonheur Children’s Hospital, Memphis, TN, United States of America,
David D SpenceLe Bonheur Children’s Hospital, Memphis, TN, United States of America,
Brian K BrightonLevine Children’s Hospital, Charlotte, NC, United States of America,
Christine ChurchillLevine Children’s Hospital, Charlotte, NC, United States of America,
Joseph A JanickiLurie Children’s Hospital of Chicago, Chicago, IL, United States of America,
Kiana KingLurie Children’s Hospital of Chicago, Chicago, IL, United States of America,
Jacob WildLurie Children’s Hospital of Chicago, Chicago, IL, United States of America,
Allan C BeebeNationwide Children’s Hospital, Columbus, OH, United States of America,
Schon CrouseNationwide Children’s Hospital, Columbus, OH, United States of America,
Teaya RoughNationwide Children’s Hospital, Columbus, OH, United States of America,
Mallory RowanNationwide Children’s Hospital, Columbus, OH, United States of America,
Satbir SinghNationwide Children’s Hospital, Columbus, OH, United States of America,
Amanda Davis-JuarezRady Children’s Hospital, San Diego, CA, United States of America,
Adam GouldRady Children’s Hospital, San Diego, CA, United States of America,
Olivia HughesRady Children’s Hospital, San Diego, CA, United States of America,
Kathleen D RickertRady Children’s Hospital, San Diego, CA, United States of America,
Vidyadhar V UpasaniRady Children’s Hospital, San Diego, CA, United States of America,
Todd J BlumbergSeattle Children’s Hospital, Seattle, WA, United States of America,
Viviana BompadreSeattle Children’s Hospital, Seattle, WA, United States of America,
Antoinette W LindbergSeattle Children’s Hospital, Seattle, WA, United States of America,
Mark L MillerSt. Louis Children’s Hospital at Washington University, St. Louis, MO, United States of America,
Jaclyn F HillTexas Children’s Hospital, Houston, TX, United States of America,
Hayley PeoplesTexas Children’s Hospital, Houston, TX, United States of America,
Scott B RosenfeldTexas Children’s Hospital, Houston, TX, United States of America,
Rod TurnerTexas Children’s Hospital, Houston, TX, United States of America,
Lawson A CopleyTexas Scottish Rite Hospital for Children/ Children’s Medical Center Dallas, Dallas, TX, United States of America,
Eduardo A LindsayTexas Scottish Rite Hospital for Children/ Children’s Medical Center Dallas, Dallas, TX, United States of America,
Brandon A RamoTexas Scottish Rite Hospital for Children/ Children’s Medical Center Dallas, Dallas, TX, United States of America,
Naureen TareenTexas Scottish Rite Hospital for Children/ Children’s Medical Center Dallas, Dallas, TX, United States of America,
R. Lane WinberlyTexas Scottish Rite Hospital for Children/ Children’s Medical Center Dallas, Dallas, TX, United States of America,
G. Ying LiUniversity of Michigan- C.S. Mott Children’s Hospital, Ann Arbor, MI, United States of America.
Jordyn SesselUniversity of Michigan- C.S. Mott Children’s Hospital, Ann Arbor, MI, United States of America.
Megan E JohnsonVanderbilt University Medical Center, Monroe Carell Jr. Children's Hospital, Nashville, TN, United States of America,
Samuel JohnsonVanderbilt University Medical Center, Monroe Carell Jr. Children's Hospital, Nashville, TN, United States of America,
Stephanie N Moore-LotridgeVanderbilt University Medical Center, Monroe Carell Jr. Children's Hospital, Nashville, TN, United States of America,
Julie SheltonVanderbilt University Medical Center, Monroe Carell Jr. Children's Hospital, Nashville, TN, United States of America,
Keith D BaldwinChildren’s Hospital of Philadelphia, Philadelphia, PA, United States of America,
Jonathan G SchoeneckerVanderbilt University Medical Center, Monroe Carell Jr. Children's Hospital, Nashville, TN, United States of America,ORCID 0000-0002-3097-5496
Children’s Orthopaedic Trauma and Infection Consortium for Evidence Based Study (CORTICES) Group
Monroe Carell Jr. Children's Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveAdequate resources are required to rapidly diagnose and treat pediatric musculoskeletal infection (MSKI). The workload MSKI consults contribute to pediatric orthopaedic services is unknown as prior epidemiologic studies are variable and negative work-ups are not included in national discharge databases. The hypothesis was tested that MSKI consults constitute a substantial volume of total consultations for pediatric orthopaedic services across the United States. STUDY

designEighteen institutions from the Children's ORthopaedic Trauma and Infection Consortium for Evidence-based Study (CORTICES) group retrospectively reviewed a minimum of 1 year of hospital data, reporting the total number of surgeons, total consultations, and MSKI-related consultations. Consultations were classified by the location of consultation (emergency department or inpatient). Culture positivity rate and pathogens were also reported.

results87,449 total orthopaedic consultations and 7,814 MSKI-related consultations performed by 229 pediatric orthopaedic surgeons were reviewed. There was an average of 13 orthopaedic surgeons per site each performing an average of 154 consultations per year. On average, 9% of consultations were MSKI related and 37% of these consults yielded positive cultures. Finally, a weak inverse monotonic relationship was noted between percent culture positivity and percent of total orthopedic consults for MSKI.

conclusionAt large, academic pediatric tertiary care centers, pediatric orthopaedic services consult on an average of ~3,000 'rule-out' MSKI cases annually. These patients account for nearly 1 in 10 orthopaedic consultations, of which 1 in 3 are culture positive. Considering that 2 in 3 consultations were culture negative, estimating resources required for pediatric orthopaedic consult services to work up and treat children based on culture positive administrative discharge data underestimates clinical need. Finally, ascertainment bias must be considered when comparing differences in culture rates from different institution's pediatric orthopaedics services, given the variability in when orthopaedic physicians become involved in a MSKI workup.

Indexed as

ChildFemaleHumansInfectionsMaleMusculoskeletal DiseasesOrthopedicsReferral and ConsultationRetrospective StudiesUnited States

Identifiers

PMID32497101
PMCPMC7272072
OpenAlexW3033197244

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.