ArticleThe Journal of infectious diseases2020
Severe Acute Respiratory Syndrome Coronavirus 2 Human Challenge Trials: Too Risky, Too Soon.
Article in The Journal of infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- When Is Social Value Proportionate to Research Risks?Bioethics · 2026Article
- Article
- The Case for Human Challenge Trials in COVID-19.Journal of bioethical inquiry · 2024Article
- Ethical acceptability of human challenge trials: Consultation with the US public and with research personnel.PloS one · 2024Article
- Risk, benefit, and social value in Covid-19 human challenge studies: pandemic decision making in historical context.Monash bioethics review · 2022Article
- Pandemic vaccine testing: Combining conventional and challenge studies.Pharmacoepidemiology and drug safety · 2022Article
- Public attitudes to a human challenge study with SARS-CoV-2: a mixed-methods study.Wellcome open research · 2022Article
- Testing SARS-CoV-2 vaccine efficacy through deliberate natural viral exposure.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2021Review
- Human Challenge Studies With Wild-Type Severe Acute Respiratory Sydrome Coronavirus 2 Violate Longstanding Codes of Human Subjects Research.Open forum infectious diseases · 2021Article
- Neutralizing Antibodies Correlate with Protection from SARS-CoV-2 in Humans during a Fishery Vessel Outbreak with a High Attack Rate.Journal of clinical microbiology · 2020Article
- SARS-CoV-2 challenge studies: ethics and risk minimisation.Journal of medical ethics · 2020Article
- Controlled human infection with SARS-CoV-2 to study COVID-19 vaccines and treatments: bioethics in Utopia.Journal of medical ethics · 2020Article
- COVID-19 Vaccines: "Warp Speed" Needs Mind Melds, Not Warped Minds.Journal of virology · 2020Review
- Neutralizing antibodies correlate with protection from SARS-CoV-2 in humans during a fishery vessel outbreak with high attack rate.medRxiv : the preprint server for health sciences · 2020Article
- Human challenge trials in vaccine development.Seminars in immunology · 2020Review
- Response to Dawson et al.The Journal of infectious diseases · 2020Article
- Is There an Ethical Upper Limit on Risks to Study Participants?Public health ethics · 2020Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.