Evidence map›Paper›PMID 32496533›Full record

ArticleNucleic acids research2020

LocalSTAR3D: a local stack-based RNA 3D structural alignment tool.

Xiaoli Chen, Nabila Shahnaz Khan, Shaojie Zhang

Abstract read
In one paragraph

Article in Nucleic acids research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Xiaoli ChenDepartment of Computer Science, University of Central Florida, Orlando, FL 32816, USA.
Nabila Shahnaz KhanDepartment of Computer Science, University of Central Florida, Orlando, FL 32816, USA.
Shaojie ZhangDepartment of Computer Science, University of Central Florida, Orlando, FL 32816, USA.

Funding

RNA Structural Motif Analysis Revisited: Towards a Systematic Understanding of Noncoding RNA as Modular BiomoleculesR01GM102515 · NIGMS · UNIVERSITY OF CENTRAL FLORIDA · PI ZHANG, SHAOJIE, ZHONG, CUNCONG · 2012 to 2025
$2.3M
NIGMS NIH HHS R01 GM102515
6 · The paper itself

Abstract

A fast-growing number of non-coding RNA structures have been resolved and deposited in Protein Data Bank (PDB). In contrast to the wide range of global alignment and motif search tools, there is still a lack of local alignment tools. Among all the global alignment tools for RNA 3D structures, STAR3D has become a valuable tool for its unprecedented speed and accuracy. STAR3D compares the 3D structures of RNA molecules using consecutive base-pairs (stacks) as anchors and generates an optimal global alignment. In this article, we developed a local RNA 3D structural alignment tool, named LocalSTAR3D, which was extended from STAR3D and designed to report multiple local alignments between two RNAs. The benchmarking results show that LocalSTAR3D has better accuracy and coverage than other local alignment tools. Furthermore, the utility of this tool has been demonstrated by rediscovering kink-turn motif instances, conserved domains in group II intron RNAs, and the tRNA mimicry of IRES RNAs.

Indexed as

Base PairingSoftwareDatabases, Nucleic AcidModels, MolecularRNASequence AlignmentSequence Analysis, RNARNA

Identifiers

PMID32496533
PMCPMC7367197

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.