Evidence map›Paper›PMID 32496390›Full record

ArticleSexually transmitted diseases2020

Latent Profile Analysis of a Syndemic of Vulnerability Factors on Incident Sexually Transmitted Infection in a Cohort of Black Men Who Have Sex With Men Only and Black Men Who Have Sex With Men and Women in the HIV Prevention Trials Network 061 Study.

Typhanye V Dyer, Rodman E Turpin, Ron Stall, Maria R Khan, LaRon E Nelson, Russell Brewer, M Reuel Friedman, Matther J Mimiaga, Robert L Cook, Conall O'Cleirigh and 1 more

Open access · greenAbstract read
In one paragraph

Article in Sexually transmitted diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.3field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pre-Exposure Prophylaxis Interventions among Black Sexual Minority Men: A Systematic Literature Review.International journal of environmental research and public health · 2022
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Sexual Risk Behavior and Lifetime HIV Testing: The Role of Adverse Childhood Experiences.International journal of environmental research and public health · 2022
    Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 9 institutions in 2 countries.

Typhanye V DyerFrom the Department of Epidemiology and Biostatistics, University of Maryland, College Park, MD.
Rodman E TurpinFrom the Department of Epidemiology and Biostatistics, University of Maryland, College Park, MD.
Ron StallDepartment of Behavioral and Community Health Sciences, University of Pittsburgh, Pittsburgh, PA.
Maria R KhanPopulation Health, New York University School of Medicine, New York, NY.
LaRon E Nelson
Russell BrewerDepartment of Medicine, University of Chicago, Chicago, IL.
M Reuel FriedmanDepartment of Behavioral and Community Health Sciences, University of Pittsburgh, Pittsburgh, PA.
Matther J MimiagaDepartment of Behavioral and Social Sciences, Brown University, Rhode Island, NY.
Robert L CookDepartment of Epidemiology, College of Public Health and Health Professions, University of Florida, Gainesville, FL.
Conall O'CleirighDepartment of Psychiatry, Massachusetts General Hospital.
Kenneth H MayerThe Fenway Institute, Harvard Medical School, Boston, MA.
University of Maryland, College Park · USUniversity of Pittsburgh · USBrown University · USHarvard University · USMassachusetts General Hospital · USNew York University · USSt. Michael's Hospital · CAUniversity of Chicago · USUniversity of Florida · US

Funding

LOC: HIV Prevention Trials NetworkUM1AI068619 · NIAID · FAMILY HEALTH INTERNATIONAL · PI Sinead Delany-Moretlwe, RAPHAEL J LANDOVITZ · 2011 to 2026
$779.5M
SDMC: HPTN 084 Pregnancy SupplementUM1AI068617 · NIAID · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Elizabeth Renata Brown, Deborah J Donnell · 2011 to 2026
$204.9M
Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
LC: HIV Prevention Trials Network - Laboratory Support for the SARS-CoV-2 Seroprevalence Study (CoVPN 5002)UM1AI068613 · NIAID · JOHNS HOPKINS UNIVERSITY · PI SUSAN H ESHLEMAN, Mark A Marzinke · 2011 to 2026
$100.2M
The impact of HIV viral diversity and cellular immunity on HIV pathogenesisP30AI060354 · NIAID · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI RAJESH T GANDHI · 2004 to 2026
$94.4M
Harvard Medical School Vaccine Clinical Trials UnitUM1AI069412 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI Lindsey Robert Baden, Daniel R. Kuritzkes · 2012 to 2026
$57.2M
Leadership for HIV/AIDS Clinical Trials Networks; HIV Prevention Trials NetworkU01AI068617 · NIAID · FRED HUTCHINSON CANCER RESEARCH CENTER · PI DONNELL, DEBORAH J · 2006 to 2010
$28.8M
Training Program for Scientists Conducting Research to Reduce HIV Health DisparitR25MH067127 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Emily A Arnold, Torsten Brian Neilands · 2003 to 2026
$5.4M
Relationship Disruption during Incarceration and HIV Risk in African American MenR01DA028766 · NIDA · UNIV OF MARYLAND, COLLEGE PARK · PI KHAN, MARIA RABIA · 2010 to 2014
$2.9M
Syndemics, STI and HIV in Black Men who Have Sex with Men and WomenR03DA037131 · NIDA · UNIV OF MARYLAND, COLLEGE PARK · PI DYER, TYPHANYE VIELKA · 2014 to 2015
$151k
NCATS NIH HHS UL1 TR001863NIAID NIH HHS P30 AI060354NIAID NIH HHS U01 AI068617NIAID NIH HHS UM1 AI068613NIAID NIH HHS UM1 AI068617NIAID NIH HHS UM1 AI068619NIAID NIH HHS UM1 AI069412NIDA NIH HHS R01 DA028766NIDA NIH HHS R03 DA037131NIMH NIH HHS R25 MH067127
6 · The paper itself

Abstract

backgroundSexually transmitted infections (STIs) are important public health concerns among black men who have sex with men only (BMSMO), as well as those who have sex with both men and women (BMSMW). Sexually transmitted infections also increase risk of acquiring and HIV, which is also a critical concern. Compared with BMSMO, research shows that BMSMW experience elevated levels of HIV/STI vulnerability factors occurring at the intrapersonal, interpersonal, and social/structural levels. These factors may work independently, increasing one's risk of engaging in high-risk sexual behaviors, but often work in a synergistic and reinforcing manner. The synergism and reinforcement of any combination of these factors are known as a syndemic, which increases HIV/STI risk.

methodsData from the HIV Prevention Trials Network (HPTN) 061 study (n = 799) was used to conduct a latent profile analysis to identify unique combinations of risk factors that may form a syndemic and that may vary between BMSMO and BMSMW. We hypothesized that the convergence of syndemic factors would differ between groups and predict sexual risk and subsequent incident STI.

resultsFor BMSMO who had a high sexual risk profile, the syndemic factors characterizing this group included perceived racism, incarceration, intimate partner violence, depression, and binge drinking. For BMSMW with a high sexual risk profile, the syndemic factors that characterized this group were incarceration, depression, and binge drinking.

conclusionsThe current analysis highlights syndemic profiles that differentiated BMSMO and BMSMW from one another and supports the need for tailored interventions that address specific syndemic factors for both subpopulations of black men who have sex with men.

Indexed as

HIV InfectionsSexual and Gender MinoritiesSexually Transmitted DiseasesBayes TheoremBlack or African AmericanFemaleHomosexuality, MaleHumansMaleRisk FactorsSexual BehaviorSyndemic

Identifiers

PMID32496390
PMCPMC7442627
OpenAlexW3031974791

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.