Evidence map›Paper›PMID 32496312›Full record

Observational studyClinical spine surgery2020

Are the Outcomes of Minimally Invasive Transforaminal/Posterior Lumbar Fusion Influenced by the Patient's Age or BMI?

Neil Manson, Ulrich Hubbe, Paulo Pereira, Khai Lam, Salvador Fuster, Wolfgang Senker

Open access · hybridAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Clinical spine surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 6 institutions in 6 countries.

Neil MansonCanada East Spine Centre and Horizon Health Network, Saint John, NB, Canada.
Ulrich HubbeClinic for Neurosurgery, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Paulo PereiraCentro Hospitalar S. Joao and Faculty of Medicine of the University of Porto, Porto, Portugal.
Khai LamAO London Bridge Spine Centre, A Spine Centre, The London Bridge Hospital, London, UK.
Salvador FusterHospital Clínic de Barcelona IBT (Institut Barceloní de Traumatologia) Clínica Corachán, Barcelona, Spain.
Wolfgang SenkerDepartment of Neurosurgery, Kepler Universitätsklinik Neuromed Campus, Johannes Kepler University Linz, Linz, Austria.
Horizon Health Network · CAHospital Clínic de Barcelona · ESKepler Universitätsklinikum · ATLondon Bridge Hospital · GBUniversidade do Porto · PTUniversity of Freiburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designA retrospective subgroup analysis of a prospective observational study was carried out. SUMMARY OF BACKGROUND DATA: Patients' baseline characteristics may influence the clinical outcomes after minimally invasive lumbar interbody fusion (MILIF).

objectiveThis study aimed to investigate the influence of patient's age and body mass index (BMI) on the clinical outcomes of MILIF for degenerative lumbar disorder. MATERIALS AND

methodsA total of 252 patients underwent MILIF. The clinical outcomes, including time to first ambulation, time to postsurgical recovery, back/leg pain in visual analog scale, Oswestry Disability Index, and EuroQol-5 Dimension, were collected at baseline, 4 weeks, 6, and 12 months. Patients were subgrouped by age (50 y and below: N=102; 51-64 y: N=102; 65 y and above: N=48) and BMI (≤25.0: N=79; 25.1-29.9: N=104; ≥30.0: N=69). Data from baseline to 12 months were compared for all clinical outcomes within age/BMI subgroups. Adverse events (AEs) and serious adverse events (SAEs) were summarized by age and BMI subgroups.

resultsAll age and BMI subgroups showed significant improvements in clinical outcomes at 12 months compared with the baseline. The median time to first ambulation was similar for all subgroups (age groups: P=0.8707; BMI: P=0.1013); older people show a trend of having longer time to postsurgical recovery (age groups: P=0.0662; BMI: P=0.1591). Oswestry Disability Index, back, and leg pain visual analog scale, and EuroQol-5 Dimension were similar in all subgroups at every timepoint. A total of 50 AEs (N=39) were reported, 9 of which were SAEs; 3 AEs and 1 SAE were considered to be related to surgical procedure. No differences were observed in safety by age groups and BMI groups.

conclusionMILIF appears to be safe and effective, independent of age or weight in the treatment of degenerative lumbar disorder. LEVEL OF EVIDENCE: Level II.

Indexed as

Lumbar VertebraeMinimally Invasive Surgical ProceduresSpinal FusionAdolescentAdultAgedAge FactorsBody Mass IndexCanadaEuropeFemaleHumansIntervertebral Disc DegenerationMaleMiddle AgedPostoperative Complications

Identifiers

PMID32496312
PMCPMC7447163
OpenAlexW3031925918

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.